Tag: Modulator|Antagonist

For research use only. We do not sell to patients. N-Desmethyl-Apalutamide CAS No. : 1332391-11-3 Biological Activity：N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and […]

For research use only. We do not sell to patients. Lurasidone-d8 CAS No. : 1132654-54-6 Biological Activity：Lurasidone-d8 is deuterium labeled Lurasidone. Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 […]

For research use only. We do not sell to patients. Lurasidone Hydrochloride CAS No. : 367514-88-3 Biological Activity：Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 […]

For research use only. We do not sell to patients. Lurasidone CAS No. : 367514-87-2 Biological Activity：Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM. Research Area：Neurological Disease Targets：Dopamine […]

For research use only. We do not sell to patients. Perospirone CAS No. : 150915-41-6 Biological Activity：Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the […]

For research use only. We do not sell to patients. LY320135 CAS No. : 176977-56-3 Biological Activity：LY320135 is a potent and selective antagonist of CB1 receptor, with a Ki of 141 nM. LY320135 also binds to 5-HT2 and muscarinic receptors with Kis of 6.4 μM and 2.1 μM, respectively. LY320135 exhibits neuroprotective effect[2]. Research Area：Neurological […]