Tag: Modulator

For research use only. We do not sell to patients. BNC210 CAS No. : 13589-06-5 Biological Activity：BNC210 (H-Ile-Trp-OH) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. BNC210 exhibits acute anxiolytic activity in rodent models of anxiety. BNC210 can be used in studies of generalised anxiety disorders. Research Area：Neurological […]

For research use only. We do not sell to patients. SMER28 CAS No. : 307538-42-7 Biological Activity：SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Research Area：Cancer Targets：Autophagy Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cancer Compound Library;Autophagy Compound Library;Protein-protein Interaction Inhibitor Library; Related Small Molecules:Physalin […]

For research use only. We do not sell to patients. JNJ-42153605 CAS No. : 1254977-87-1 Biological Activity：JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM. Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library; Related […]

For research use only. We do not sell to patients. LRH-1 modulator-1 CAS No. : 2244781-29-9 Biological Activity：LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 shows anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces anti-inflammatory cytokine IL-10, and reduces inflammatory cytokine IL-1b and TNFa. Research Area：Inflammation/Immunology Targets：Others Related Small […]

For research use only. We do not sell to patients. SNIPER(ER)-87 CAS No. : 2222354-91-6 Biological Activity：SNIPER(ER)-87 consists of an inhibitor of apoptosis protein (IAP) ligand LCL161 derivative that is conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen by a PEG linker, and efficiently degrades the ERα protein (IC50=0.097 μM). SNIPER(ER)-87 preferentially recruits XIAP […]

For research use only. We do not sell to patients. Raloxifene-d4 Bismethyl Ether CAS No. : 1185006-58-9 Biological Activity：Raloxifene-d4 Bismethyl Ether is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used […]

For research use only. We do not sell to patients. Parathyroid Hormone (1-34), human, biotinylated Biological Activity：Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns[2]. Research […]

For research use only. We do not sell to patients. Prednisolone Tebutate CAS No. : 7681-14-3 Biological Activity：Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant. Research Area：Inflammation/Immunology|Endocrinology Targets：Glucocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound […]

For research use only. We do not sell to patients. TCMDC-125431 Biological Activity：TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. [Met(O)21] Corticotropin Releasing Factor, ovine Biological Activity：[Met(O)21] Corticotropin Releasing Factor, ovine is a corticotropin releasing factor isolated from ovine hypothalamic extracts. Corticotropin releasing factor (CRF) is a hypothalamic hormone, which stimulates the secretion of adrenocorticotrophic hormone (ACTH). Research Area：Endocrinology Targets：CRFR Related Small Molecules:Stresscopin-related peptide (human);Sauvagine;CRF(6-33)(human) […]