Tag: Modulator

For research use only. We do not sell to patients. DPI 201-106 CAS No. : 97730-95-5 Biological Activity：DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect[2][3]. Research Area：Cardiovascular Disease Targets：Sodium Channel […]

For research use only. We do not sell to patients. Bombesin CAS No. : 31362-50-2 Biological Activity：Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors. Research Area：Metabolic Disease|Neurological Disease Targets：Bombesin Receptor Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:PD176252;RC-3095;BA 1;BIM-26226;ML-18;Kuwanon H;MK-5046;Litorin;Ranatensin;Kuwanon […]

For research use only. We do not sell to patients. Raloxifene 6-glucuronide-d4 CAS No. : 2021255-70-7 Biological Activity：Raloxifene 6-glucuronide-d4 is the deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene […]

For research use only. We do not sell to patients. AT-1002 TFA Biological Activity：AT-1002 TFA, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer[2]. Research Area：Metabolic Disease Targets：Gap Junction Protein Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Covalent Screening Library;Cytoskeleton Compound Library; Related Small Molecules:Meclofenamic acid sodium hydrate;Gap 26;Carbenoxolone disodium;Meclofenamic acid-13C6;Larazotide […]

For research use only. We do not sell to patients. COR170 CAS No. : 1048039-15-1 Biological Activity：COR170 (11u) is a selective CB2 inverse-agonist which is a 4-quinolone-3-carboxylic acid derivative with a Ki value of 3.8 nM for CB2 receptor. COR170 can be used for the research of inflammation and neuroprotection[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：Cannabinoid Receptor […]

For research use only. We do not sell to patients. RCGD423 CAS No. : 108237-91-8 Biological Activity：RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair. Research Area：Inflammation/Immunology|Neurological Disease Targets：Interleukin Related Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library; Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist […]

For research use only. We do not sell to patients. Sonlicromanol CAS No. : 1541170-75-5 Biological Activity：Sonlicromanol (KH176) is an orally active reactive oxygen species (ROS) modulator for the study in mitochondrial disease[2]. Research Area：Metabolic Disease Targets：Reactive Oxygen Species Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Chitoheptaose heptahydrochloride;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor 3;CYPMPO;Antioxidant agent-5;ROS-ERS inducer 1;Glucosamine-13C hydrochloride;L-Ascorbic acid sodium salt;D-Isofloridoside;L-Carnitine-d3 […]

For research use only. We do not sell to patients. di-Ellipticine-RIBOTAC CAS No. : 2767983-76-4 Biological Activity：di-Ellipticine-RIBOTAC is a dual-function small molecule that reduces c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo amyotrophic lateral sclerosis (ALS ) models. Research Area：Neurological Disease Targets：PROTACs Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC […]

For research use only. We do not sell to patients. Insulin levels modulator CAS No. : 1019254-94-4 Biological Activity：Insulin levels modulator could be used to treat diabetes. Research Area：Metabolic Disease|Endocrinology Targets：Insulin Receptor Related Small Molecules:AGL-2263;KU14R;SU4984;HNMPA-(AM)3;S961 TFA;OI338;Gastric Inhibitory Peptide, porcine;MSDC 0160;[Tyr0] Gastric Inhibitory Peptide (23-42), human;AVJ16;GIP, human;GSK1838705A;DA-JC4;MSDC-0602K;AG1024;MID-1;(Pro3) GIP, human;HNMPA;BMS-754807;GSK1904529A;NVP-ADW742;Linsitinib-d3;GIP (1-30) amide,human acetate Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. Acetylarenobufagin CAS No. : 184673-79-8 Biological Activity：Acetylarenobufagin is a steroidal hypoxia inducible factor-1 (HIF-I) modulator. Research Area：Cancer Targets：HIF/HIF Prolyl-Hydroxylase Related Small Molecules:TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;AKBA;LW6;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;HIF-1/2α-IN-1;Roxadustat;Daprodustat;Zifcasiran;Acriflavine hydrochloride;BAY 87-2243;PHD-1-IN-1;PT-2385;ZINC13466751;(Rac)-Dencichine;Enarodustat;HIF-2α-IN-6;ENMD-1198 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  […]