Tag: Modulator

For research use only. We do not sell to patients. Diguanosine 5′-triphosphate lithium Biological Activity：Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphates. Diguanosine 5′-triphosphate lithium also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate lithium is needed for the synthesis of RNA during the transcription process[2]. Research Area：Cancer Targets：Nucleoside Antimetabolite/Analog|DNA/RNA Synthesis Related Small Molecules:m7GpppCpG;Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;m7GpppUmpG;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor […]

For research use only. We do not sell to patients. Raloxifene-d10 Biological Activity：Raloxifene-d10 is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research. Research Area：Cancer […]

For research use only. We do not sell to patients. ONO-8590580 CAS No. : 1802661-73-9 Biological Activity：ONO-8590580 is a GABAA α5 negative allosteric modulator. Research Area：Neurological Disease Targets：GABA Receptor Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;GABA Receptor […]

For research use only. We do not sell to patients. Bazedoxifene acetate CAS No. : 198481-33-3 Biological Activity：Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate […]

For research use only. We do not sell to patients. SRI-37240 CAS No. : 883956-47-6 Biological Activity：SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418. […]

For research use only. We do not sell to patients. Raloxifene-d4 hydrochloride CAS No. : 1188263-47-9 Biological Activity：Raloxifene-d4 hydrochloride is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast […]

For research use only. We do not sell to patients. MRGPRX4 modulator-2 CAS No. : 2492595-24-9 Biological Activity：MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s […]

For research use only. We do not sell to patients. Estetrol-d4 Biological Activity：Estetrol-d4 is the deuterium labeled Estetrol. Estetrol, a natural estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on […]

For research use only. We do not sell to patients. gamma-secretase modulator 3 CAS No. : 1431697-84-5 Biological Activity：gamma-secretase modulator 3 is a gamma-secretase modulator. Research Area：Neurological Disease Targets：γ-secretase Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:γ-Secretase modulator 4;ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;Aβ42-IN-2;DAPT (GMP);BPN-15606;LY-411575 (isomer 3);BMS 433796;YO-01027 (GMP);BI-1408;Nirogacestat dihydrobromide;gamma-secretase modulator 1 […]

For research use only. We do not sell to patients. NOT Receptor Modulator 1 CAS No. : 1015231-98-7 Biological Activity：NOT Receptor Modulator 1 is a nuclear receptor NOT modulator extracted from patent WO 2008034974 A1, Example 39 in table1. Research Area：Neurological Disease Targets：Others Related Screening Libraries:Bioactive Compound Library Plus;Nuclear Receptor Compound Library; Related Small Molecules:Immune […]