Tag: Modulator

For research use only. We do not sell to patients. FGFR-IN-7 CAS No. : 2488764-17-4 Biological Activity：FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research. Research Area：Neurological […]

For research use only. We do not sell to patients. Sirtuin modulator 3 CAS No. : 708995-11-3 Biological Activity：Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative, acts as a sirtuin modulator. Research Area：Cancer|Metabolic Disease|Inflammation/Immunology Targets：Sirtuin Related Small Molecules:PROTAC Sirt2 Degrader-1;SIRT1/2/3-IN-1;Cambinol;JGB1741;Nicotinamide-d4;Resveratrol;SRT 1720 Hydrochloride;Sirtuin modulator 2;SIRT1-IN-3;SRT 2104;Tenovin-6;SirReal2;Ganoderic acid D;MC3482;Dihydrocoumarin;AK-1;SIRT2-IN-9;JFD00244;OSS_128167;Inauhzin;SRT 2183;SRTCX1002;Nicotinamide riboside;3-TYP;SIRT-IN-2;CHIC35;SIRT1 activator 3;SRT3657;Resveratrol-d4 Trending products：Recombinant […]

For research use only. We do not sell to patients. Dihydrotachysterol CAS No. : 67-96-9 Biological Activity：Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [2]. Research Area：Metabolic Disease Targets：VD/VDR Related […]

For research use only. We do not sell to patients. PYD-106 CAS No. : 1560894-05-4 Biological Activity：PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and […]

For research use only. We do not sell to patients. GTx-007 CAS No. : 401900-40-1 Biological Activity：GTx-007 (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. GTx-007 (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity[2]. Research Area：Cancer […]

For research use only. We do not sell to patients. Mutant p53 modulator-1 CAS No. : 2746371-35-5 Biological Activity：Mutant p53 modulator-1 is a mutant p53 modulator. Mutant p53 modulator-1 reduces the progression of cancers that contain a p53 mutation (extracted from patent WO2021231474A1, compound 231B). Research Area：Cancer Targets：MDM-2/p53 Related Small Molecules:MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor […]

For research use only. We do not sell to patients. Pedunculoside CAS No. : 42719-32-4 Biological Activity：Pedunculoside exerts lipid-lowering effects partly through the regulation of lipogenesis and fatty acid β-oxidation. Research Area：Metabolic Disease Targets：Fatty Acid Synthase (FASN) Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Natural Product Library;Glycoside Compound Library;Terpenoids Library;Traditional Chinese Medicine Active Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. Ingenol Mebutate CAS No. : 75567-37-2 Biological Activity：Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor […]

For research use only. We do not sell to patients. JAMI1001A CAS No. : 1001019-46-0 Biological Activity：JAMI1001A is a positive allosteric modulator of AMPA receptor. JAMI1001A efficaciously modulates AMPA receptor deactivation and desensitization of both flip and flop receptor isoforms. Research Area：Neurological Disease Targets：iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 […]

For research use only. We do not sell to patients. Dihydroresveratrol CAS No. : 58436-28-5 Biological Activity：Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations. Research Area：Cancer Targets：Estrogen Receptor/ERR Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Natural Product […]