Tag: Modulator

For research use only. We do not sell to patients. Posenacaftor sodium CAS No. : 2095064-06-3 Biological Activity：Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF). Research Area：Inflammation/Immunology Targets：CFTR Related Screening Libraries:Covalent Screening Library […]

For research use only. We do not sell to patients. Theaflavine-3,3′-digallate CAS No. : 33377-72-9 Biological Activity：Theaflavine-3,3′-digallate, a bioactive black tea phenolic, can be used for the research of gut microbiota composition modulatory effects. Research Area：Metabolic Disease|Infection Targets：Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Arazine CAS No. : 135304-07-3 Biological Activity：Arazine (N-Acetyl-S-farnesyl-L-cysteine) is a cell-permeable modulator of G protein and G-protein coupled receptor signaling. Arazine can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Research Area：Inflammation/Immunology Targets：Others Related Small Molecules:Immune […]

For research use only. We do not sell to patients. Bradykinin (1-6) CAS No. : 23815-88-5 Biological Activity：Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY). Research Area：Cardiovascular Disease|Endocrinology Targets：Bradykinin Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Anti-Cardiovascular Disease Compound Library;Endocrinology Compound […]

For research use only. We do not sell to patients. Toll-like receptor modulator CAS No. : 926927-42-6 Biological Activity：Toll-like receptor modulator is a modulator of TLR7/8, which modulates immune function. Research Area：Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library; Related […]

For research use only. We do not sell to patients. Mitochondrial fusion promoter M1 CAS No. : 219315-22-7 Biological Activity：Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury[2][3]. […]

For research use only. We do not sell to patients. Fmoc-leucine-d3 CAS No. : 538372-74-6 Biological Activity：Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. […]

For research use only. We do not sell to patients. C108297 CAS No. : 864972-30-5 Biological Activity：C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding Ki 0.7 nM; GR reporter gene functional Ki 0.6 nM). C108297 attenuates obesity by reducing caloric intake and increasing lipolysis and fat oxidation, and in addition attenuates inflammation[2]. Research […]

For research use only. We do not sell to patients. 16,16-Dimethyl prostaglandin E2 CAS No. : 39746-25-3 Biological Activity：16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway[2]. Research Area：Inflammation/Immunology Targets：Prostaglandin Receptor Related […]

For research use only. We do not sell to patients. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) CAS No. : 77128-69-9 Biological Activity：[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of […]