Tag: Modulator

For research use only. We do not sell to patients. Flibanserin CAS No. : 167933-07-5 Biological Activity：Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin […]

For research use only. We do not sell to patients. N-(3-Oxohexanoyl)-L-homoserine lactone CAS No. : 143537-62-6 Biological Activity：N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing. Research Area：Infection|Inflammation/Immunology Targets：Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent […]

For research use only. We do not sell to patients. O-Phospho-L-serine CAS No. : 407-41-0 Biological Activity：O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist […]

For research use only. We do not sell to patients. Cariprazine CAS No. : 839712-12-8 Biological Activity：Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor Related Screening Libraries:Drug […]

For research use only. We do not sell to patients. Sirtuin modulator 5 CAS No. : 694469-31-3 Biological Activity：Sirtuin modulator 5 is a sirtuin modulating agent. Sirtuin modulator 5 can activate SIRT1 with a DC50 value of

For research use only. We do not sell to patients. Carboxy Gliclazide-d4 CAS No. : 1346602-90-1 Biological Activity：Carboxy Gliclazide-d4 is the deuterium labeled Carboxy Gliclazide. Research Area：Infection Targets：Drug Metabolite Related Small Molecules:Nicotinamide N-oxide;4-Hydroxyphenylbutazone;Ampyrone;Resveratrol-3-O-sulfate sodium;Sonidegib metabolite M48;Isonicotinic acid;Cycloguanil hydrochloride;Hydroxytanshinone IIA;Endoxifen;Fodipir;Regorafénib N-oxyde (M2)-13C,d3;AZ7550 Mesylate;AR-13324 M1 metabolite;Thyroxine sulfate;Netupitant metabolite Monohydroxy Netupitant;(-)-(E)-Guggulsterone;Leukotriene D4;Desbutyl Lumefantrine;(R)-3-Hydroxy Midostaurin;RP101442;Paeoniflorgenin;PR-104A;HMMNI-d3;Ilaprazole sulfone Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Tebanicline dihydrochloride CAS No. : 209326-19-2 Biological Activity：Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM. Research Area：Neurological Disease Targets：nAChR Related Screening Libraries:Covalent Screening […]

For research use only. We do not sell to patients. Etiocholanolone CAS No. : 53-42-9 Biological Activity：Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form[2]. Research Area：Neurological Disease Targets：GABA Receptor|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Danegaptide CAS No. : 943134-39-2 Biological Activity：Danegaptide (GAP-134) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect[2]. Research Area：Cardiovascular Disease Targets：Gap Junction Protein Related Small Molecules:AT-1002 TFA;Meclofenamic acid sodium hydrate;Gap 26;Carbenoxolone disodium;Meclofenamic acid-13C6;Larazotide acetate;Meclofenamic acid-d4;Danegaptide Hydrochloride;Rotigaptide;Gap19;TAT-Gap19 TFA;Tonabersat;Peptide5;Gap 27;Meclofenamic acid sodium Trending […]

For research use only. We do not sell to patients. THS-044 CAS No. : 62054-67-5 Biological Activity：THS-044 binding stabilizes the HIF2(alpha) PAS-B folded state, for regulating HIF2 activity in endogenous and clinical settings. Research Area：Cancer Targets：HIF/HIF Prolyl-Hydroxylase Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Oxygen Sensing Compound Library;Glutamine Metabolism […]