Tag: Modulator

For research use only. We do not sell to patients. Bazedoxifene-d4 CAS No. : 1133695-49-4 Biological Activity：Bazedoxifene-d4 is deuterium labeled Bazedoxifene. Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. […]

For research use only. We do not sell to patients. Vanzacaftor CAS No. : 2374124-49-7 Biological Activity：Vanzacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) for treating cystic fibrosis. Research Area：Inflammation/Immunology Targets：CFTR Related Small Molecules:PG01;CFTR corrector 8;CP-628006;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;CFTR corrector 4;Posenacaftor sodium;NJH-2-057;KM11060;Nesolicaftor;Galicaftor;Tezacaftor;PPQ-102;SRI-41315;CFTR corrector 6 Trending products：Recombinant […]

For research use only. We do not sell to patients. IL-17 modulator 3 CAS No. : 2467731-88-8 Biological Activity：IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases. Research Area：Cancer|Inflammation/Immunology Targets：Interleukin Related Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine […]

For research use only. We do not sell to patients. gamma-secretase modulator 1 hydrochloride Biological Activity：gamma-secretase inhibitior-1 is a gamma-secretase modulator, γ-secretase inhibitior-1 is useful for Alzheimer’s disease. Research Area：Neurological Disease Targets：γ-secretase Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Aging Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library; Related Small […]

For research use only. We do not sell to patients. CFTR corrector 4 CAS No. : 1918142-34-3 Biological Activity：CFTR corrector 4 (Compound 13), an active (R,R)-form enantiomer, is a highly potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. CFTR corrector 4 can increase CFTR levels at the cell surface and have the […]

For research use only. We do not sell to patients. Gevokizumab CAS No. : 1129435-60-4 Biological Activity：Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor […]

For research use only. We do not sell to patients. IL-17 modulator 1 CAS No. : 2446803-85-4 Biological Activity：IL-17 modulator 1 is an orally active, highly efficacious small molecule IL-17 modulators extracted from patent WO 2020127685. IL-17 modulator 1 can be used for the research of preventing, treating or ameliorating a variety of diseases including […]

For research use only. We do not sell to patients. DCB CAS No. : 6971-97-7 Biological Activity：DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect […]

For research use only. We do not sell to patients. Autotaxin modulator 1 CAS No. : 1548743-69-6 Biological Activity：Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as […]

For research use only. We do not sell to patients. 3’Ome-m7GpppAmpG ammonium Biological Activity：3’Ome-m7GpppAmpG ammonium is a trinucleotide Cap analogue containing a locked nucleic acid (LNA) molecule. 3’Ome-m7GpppAmpG ammonium shows a significant translational efficiency. 3’Ome-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such […]