Tag: Modulator

For research use only. We do not sell to patients. Org-26576 CAS No. : 1026791-61-6 Biological Activity：Org-26576 is a AMPA receptor positive allosteric modulator. Research Area：Neurological Disease Targets：iGluR Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library; Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 […]

For research use only. We do not sell to patients. Piracetam-d6 Biological Activity：Piracetam-d6 is deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. Research Area：Neurological Disease Targets：iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 hydrochloride;DL-Phenylalanine-d5 […]

For research use only. We do not sell to patients. AMG-3969 CAS No. : 1361224-53-4 Biological Activity：AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM. Research Area：Metabolic Disease Targets：Glucokinase Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:PF-04937319;Globalagliatin;Palmitelaidic Acid;Glucokinase activator 1;AZD1656;RO-28-1675;IHVR-11029;Cadisegliatin;PSN-GK1;Glucokinase activator 3;PF-04991532;Dorzagliatin;AR453588 hydrochloride;GKA50 quarterhydrate;AMG-1694;Palmitelaidic acid-d13;BMS-820132;MK-0941 free base;AM-2394 […]

For research use only. We do not sell to patients. SR2595 CAS No. : 1415252-61-7 Biological Activity：SR2595 is an inverse agonist of PPARγ with an IC50 of 30 nM. Research Area：Metabolic Disease Targets：PPAR Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;Mifobate;Daidzein-d4;Ciglitazone;MK-886;CP-775146;FK614;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;Norathyriol;Saroglitazar;GW 9578;Elafibranor;ST247;Bilobetin Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. VU 0360223 CAS No. : 1274859-33-4 Biological Activity：VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;L-AP3;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU […]

For research use only. We do not sell to patients. Ac-SVVVRT-NH2 CAS No. : 1401804-69-0 Biological Activity：Ac-SVVVRT-NH2 is a PGC-1α modulator that modulates the activity of the human PGC-1α promoter (114%). Ac-SVVVRT-NH2 increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 can be used in the research of diseases […]

For research use only. We do not sell to patients. Ogerin CAS No. : 1309198-71-7 Biological Activity：Ogerin is a selective GPR68 positive aliasing modulator (PAM) (pEC50=6.83) with a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-β-induced myofibroblast differentiation of fibroblasts from multiple organ systems. […]

For research use only. We do not sell to patients. Rotigaptide CAS No. : 355151-12-1 Biological Activity：Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability […]

For research use only. We do not sell to patients. α-Helical CRF(9-41) CAS No. : 90880-23-2 Biological Activity：α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[2]. Research Area：Neurological Disease Targets：CRFR Related Small Molecules:Stresscopin-related peptide (human);Sauvagine;CRF(6-33)(human) […]

For research use only. We do not sell to patients. Carbidopa monohydrate CAS No. : 38821-49-7 Biological Activity：Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson’s disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth[2]. Research Area：Cancer|Neurological Disease […]