Tag: Modulator

For research use only. We do not sell to patients. Tonlamarsen CAS No. : 2589926-20-3 Biological Activity：Tonlamarsen is a angiotensinogen synthesis reducer, with antihypertensive activity. Research Area：Cardiovascular Disease Targets：Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone monosulfate sodium;25-Hydroxycholesterol-d6;Pyrroloquinoline quinone;Roridin L2;NAPQI;Imidazole;Adipokinetic hormone I (Locusta migratoria) Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Mavacamten CAS No. : 1642288-47-8 Biological Activity：Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Research Area：Cardiovascular Disease Targets：Myosin Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. CFTR corrector 9 CAS No. : 909861-78-5 Biological Activity：CFTR corrector 9 (compound 42) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator. CFTR corrector 9 can be used for researching cystic fibrosis (CF) and other CFTR associated disorders. Research Area：Others Targets：CFTR Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. Ospemifene CAS No. : 128607-22-7 Biological Activity：Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with Kis of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer[2]. Research Area：Cancer […]

For research use only. We do not sell to patients. Danegaptide Hydrochloride CAS No. : 943133-81-1 Biological Activity：Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect[2]. Research Area：Cardiovascular Disease Targets：Gap Junction Protein Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Clinical Compound Library;Peptidomimetic […]

For research use only. We do not sell to patients. ASN04421891 CAS No. : 570365-12-7 Biological Activity：ASN04421891 is a potent GPR17 receptor modulator, with an EC50 of 3.67 nM in [35S]GTPγS binding assay. ASN04421891 can be used for neurodegenerative diseases research. Research Area：Neurological Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide […]

For research use only. We do not sell to patients. P34cdc2 Kinase Fragment CAS No. : 309247-52-7 Biological Activity：P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis[2]. Research Area：Others Targets：Microtubule/Tubulin Related Small Molecules:Tirbanibulin dihydrochloride;Tilavonemab;Tau […]

For research use only. We do not sell to patients. Meranzin CAS No. : 23971-42-8 Biological Activity：Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the […]

For research use only. We do not sell to patients. TLX agonist 1 CAS No. : 958323-31-4 Biological Activity：TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity. Research Area：Cancer|Neurological Disease Targets：Others Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cancer Compound Library;Nuclear […]

For research use only. We do not sell to patients. Glycycoumarin CAS No. : 94805-82-0 Biological Activity：Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[2]. Research Area：Cancer Targets：Keap1-Nrf2|AMPK […]