Tag: Modulator

For research use only. We do not sell to patients. CXCR7 modulator 1 CAS No. : 2231812-31-8 Biological Activity：CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM. Research Area：Endocrinology Targets：CXCR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology […]

For research use only. We do not sell to patients. Arzoxifene CAS No. : 182133-25-1 Biological Activity：Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on […]

For research use only. We do not sell to patients. Substance P CAS No. : 33507-63-0 Biological Activity：Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor|Endogenous Metabolite Related Screening […]

For research use only. We do not sell to patients. IL-17A modulator-1 CAS No. : 2748749-29-1 Biological Activity：IL-17A modulator-1 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 9. IL-17A modulator-1 inhibits the biological action of IL-17A with a pIC50 of 8.2. IL-17A modulator-1 can be used for the research of diseases or disorders associated […]

For research use only. We do not sell to patients. AMPA receptor modulator-2 CAS No. : 2034181-36-5 Biological Activity：AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor. pIC50 = -lgIC50. Research Area：Others Targets：iGluR Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling […]

For research use only. We do not sell to patients. RG7800 CAS No. : 1449598-06-4 Biological Activity：RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment. Research Area：Others Targets：DNA/RNA Synthesis Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Orally Active Compound Library;Targeted […]

For research use only. We do not sell to patients. Bazedoxifene hydrochloride CAS No. : 198480-56-7 Biological Activity：Bazedoxifene hydrochloride (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene hydrochloride can be used for the research of osteoporosis. […]

For research use only. We do not sell to patients. DK1 CAS No. : 1187568-17-7 Biological Activity：DK1 is a potent modulator of estrogen related receptor. DK1 has an ability in reducing blood glucose, and impacts the activity of ERRα receptor. DK1 has the potential for the research of diabetes. Research Area：Metabolic Disease Targets：Estrogen Receptor/ERR Related […]

For research use only. We do not sell to patients. Betamethasone acibutate CAS No. : 5534-05-4 Biological Activity：Betamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid. Research Area：Inflammation/Immunology|Endocrinology Targets：Glucocorticoid Receptor Related Small Molecules:Deflazacort-D5;Glucocorticoid receptor agonist-2;AZD2906;Beclometasone dipropionate;ORIC-101;Clobetasone butyrate;Cortisone-d2;Clobetasone butyrate-d7;Cortisone-13C3;Glucocorticoid receptor agonist;Cortodoxone-d2;Hydrocortisone aceponate;Glucocorticoid receptor-IN-2;OP-3633;GW-870086;Nenocorilant;Hydrocortisone cypionate;Corticosterone-d8;21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione;Deflazacort-d5-1;Mapracorat;Hydrocortisone-d4;Hydrocortisone acetate Trending products：Recombinant Proteins  |  Bioactive Screening […]

For research use only. We do not sell to patients. SK3 Channel-IN-1 CAS No. : 2396571-04-1 Biological Activity：SK3 Channel-IN-1 (compound 7a) is a potent and specific SK3 channel modulator. SK3 Channel-IN-1 has efficient effect on breast cancer MDA-MB-435 cell migration while exhibiting low cytotoxicity in other cell lines. SK3 Channel-IN-1 can modulate ion channels’activity in […]