Diguanosine 5′-triphosphate

For research use only. We do not sell to patients. Diguanosine 5′-triphosphate CAS No. : 6674-45-9 Biological Activity:Diguanosine 5′-triphosphate (Gp3G) is a dinucleoside triphosphates. Diguanosine 5′-triphosphate also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate is needed for the synthesis of RNA during the transcription process[2]. Research Area:Cancer Targets:Nucleoside Antimetabolite/Analog|DNA/RNA Synthesis Related Small Molecules:m7GpppCpG;Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;m7GpppUmpG;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor […]

S-23

For research use only. We do not sell to patients. S-23 CAS No. : 1010396-29-8 Biological Activity:S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats[2]. […]

Chlorzoxazone-d3

For research use only. We do not sell to patients. Chlorzoxazone-d3 CAS No. : 1185173-60-7 Biological Activity:Chlorzoxazone-d3 is the deuterium labeled Chlorzoxazone. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a […]

1-BCP

For research use only. We do not sell to patients. 1-BCP CAS No. : 34023-62-6 Biological Activity:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents. 1-BCP is a memory-enhancing agent[2]. Research Area:Neurological Disease Targets:iGluR Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound […]

8α,9α-Epoxycoleon-U-quinone

For research use only. We do not sell to patients. 8α,9α-Epoxycoleon-U-quinone CAS No. : 93800-59-0 Biological Activity:8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer […]

LY-404187

For research use only. We do not sell to patients. LY-404187 CAS No. : 211311-95-4 Biological Activity:LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors, with the EC50s of 5.65, 0.15, 1.44, 1.66 and 0.21 µM for GluR1i, GluR2i, GluR2o, GluR3i and GluR4i, respectively. LY-404187 has therapeutic potential in a […]

GNE-8324

For research use only. We do not sell to patients. GNE-8324 CAS No. : 1698901-76-6 Biological Activity:GNE-8324 is a selective GluN2A positive allosteric modulator. GNE-8324 selectively enhances NMDA receptor (NMDAR)-mediated synaptic responses in inhibitory but not excitatory neurons. Research Area:Neurological Disease Targets:iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 hydrochloride;DL-Phenylalanine-d5 hydrochloride;NMDA;CFM-2;Lanicemine […]

GAT564

For research use only. We do not sell to patients. GAT564 Biological Activity:GAT564 (Compound 15d) is a potent allosteric modulator of cannabinoid 1 receptor (CB1R) with EC50s of 87 and 320 nM respectively for cAMP and β-arrestin2. GAT564 markedly promotes orthosteric ligand binding to hCB1R. GAT564 is efficacious as a topical agent that significantly reduces […]

CB1R Allosteric modulator 2

For research use only. We do not sell to patients. CB1R Allosteric modulator 2 CAS No. : 2513102-64-0 Biological Activity:CB1R Allosteric modulator 2 (compound 18) is a potent CB1R allosteric modulator. CB1R Allosteric modulator 2 shows negatively affects the functional activity of orthosteric ligands (NAM) at CB1Rs. Research Area:Others Targets:Cannabinoid Receptor Related Small Molecules:Pregnenolone monosulfate […]

VU0119498

For research use only. We do not sell to patients. VU0119498 CAS No. : 79183-37-2 Biological Activity:VU0119498 is a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM), with EC50s of 6.04, 6.38, and 4.08 µM, respectively. VU0119498 has antidiabetic activity[2][3]. Research Area:Metabolic Disease Targets:mAChR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal […]