Tag: Modulator

For research use only. We do not sell to patients. Fmoc-Ala-OH-13C3 CAS No. : 765259-05-0 Biological Activity：Fmoc-Ala-OH-13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind Research Area：Metabolic Disease Targets：PPAR Related Small Molecules:Falcarindiol;5-Aminosalicylic […]

For research use only. We do not sell to patients. Shield-1 CAS No. : 914805-33-7 Biological Activity：Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization […]

For research use only. We do not sell to patients. LY377604 CAS No. : 204592-94-9 Biological Activity：LY377604 is a human β3-adrenergic receptor agonist with an EC50 of 2.4 nM and also a β1– and β2-adrenergic receptor antagonist. Research Area：Metabolic Disease|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine […]

For research use only. We do not sell to patients. TH1217 CAS No. : 1862212-48-3 Biological Activity：TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity […]

For research use only. We do not sell to patients. Endosidin-2 CAS No. : 1839524-44-5 Biological Activity：Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. […]

For research use only. We do not sell to patients. m7GpppAmpG CAS No. : 62858-30-4 Biological Activity：m7GpppAmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90%. Research Area：Others Targets：DNA/RNA Synthesis Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Risdiplam;TH287 hydrochloride;Direct Black 38;7-TFA-ap-7-Deaza-ddA;BCH001;NKP-1339;Fialuridine;2′-O-MOE-5-Me-rC;PTC299;2′-F-Bz-dC Phosphoramidite Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. 3’Ome-m7GpppAmpG CAS No. : 2089461-55-0 Biological Activity：3’Ome-m7GpppAmpG is a trinucleotide Cap analogue containing a locked nucleic acid (LNA) molecule. 3’Ome-m7GpppAmpG shows a significant translational efficiency. 3’Ome-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such […]

For research use only. We do not sell to patients. LH-RH II (chicken) CAS No. : 91097-16-4 Biological Activity：LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken[2]. […]

For research use only. We do not sell to patients. IDRA 21 CAS No. : 22503-72-6 Biological Activity：IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging. Research […]

For research use only. We do not sell to patients. IMD-vanillin Biological Activity：IMD-vanillin is a novel imidazoquinolinone-NF-κB immunomodulator dimers. Research Area：Cancer Targets：NF-κB Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920;Armepavine;Laquinimod;S-Allylmercaptocysteine Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  […]