Tag: Modulator

For research use only. We do not sell to patients. γ-Secretase modulator 4 CAS No. : 1420200-82-3 Biological Activity：γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively. Research Area：Neurological Disease Targets：γ-secretase Related Small Molecules:ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator […]

For research use only. We do not sell to patients. Kv3 modulator 2 CAS No. : 2101321-76-8 Biological Activity：Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders. Research Area：Inflammation/Immunology Targets：Potassium Channel […]

For research use only. We do not sell to patients. Ginsenoside F3 CAS No. : 62025-50-7 Biological Activity：Ginsenoside F3, a component of PPTGs (an minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10). Research […]

For research use only. We do not sell to patients. CFTR corrector 8 CAS No. : 1918142-35-4 Biological Activity：CFTR corrector 8 is a potent CFTR modulator. CFTR can be used in the research of cystic fibrosis. Research Area：Inflammation/Immunology Targets：CFTR Related Small Molecules:PG01;CP-628006;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;Vanzacaftor;CFTR corrector 4;Posenacaftor sodium;NJH-2-057;KM11060;Nesolicaftor;Galicaftor;Tezacaftor;PPQ-102;SRI-41315;CFTR corrector […]

For research use only. We do not sell to patients. IMD-ferulic Biological Activity：IMD-ferulic is a covalently linked NF-κB modulator that improves the adjuvanticity of small molecule immune potentiators. Research Area：Cancer Targets：NF-κB Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920;Armepavine;Laquinimod;S-Allylmercaptocysteine Trending products：Recombinant […]

For research use only. We do not sell to patients. MK-6884 CAS No. : 2102194-04-5 Biological Activity：MK-6884 is a M4 muscarinic receptor positive allosteric modulator (PAM) with a Ki value of 0.19 nM. MK-6884 can be used for the research of the neurodegenerative diseases. MK-6884 can be conveniently radiolabeled with carbon-11 and as a positron […]

For research use only. We do not sell to patients. Biricodar CAS No. : 159997-94-1 Biological Activity：Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells. Research Area：Cancer Targets：P-glycoprotein Related Small Molecules:P-gp inhibitor 4;Sinapine thiocyanate;Dofequidar fumarate;Elacridar;Coniferyl ferulate;Anticancer agent 50;Valspodar;P-gp inhibitor 1;Boeravinone B;Solamargine;Polyoxyethylene stearate;TTT-28;CP-100356 hydrochloride;Epoxylathyrol;Chrysosplenetin;Zamicastat;Tariquidar;P-gp modulator 3;Roemerine;Coleon-U-quinone;Zosuquidar trihydrochloride;Encequidar;P-gp modulator […]

For research use only. We do not sell to patients. mGluR2 modulator 1 CAS No. : 2671063-84-4 Biological Activity：mGluR2 modulator 1 (compound 95) is a potent and BBB-penetrated mGluR2 (metabotropic glutamate receptor-2) positive allosteric modulator, with an EC50 of 0.03 μM. mGluR2 modulator 1 can be used for psychosis research. Research Area：Neurological Disease Targets：mGluR Related […]

For research use only. We do not sell to patients. Alpidem CAS No. : 82626-01-5 Biological Activity：Alpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect. Research Area：Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Adipiplon;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric acid-d6;Ginsenoside Rc;Fipronil;p-Hydroxybenzaldehyde-13C;Lesogaberan hydrochloride;FG 7142;Isoguvacine hydrochloride;Guvacine ethyl ester;MRK-623;Rilmazafone;(-)-α-Pinene;Alpidem-d14;17-PA Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. TM-25659 CAS No. : 260553-97-7 Biological Activity：TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities. Research Area：Metabolic Disease Targets：Others Related Screening Libraries:Bioactive Compound Library Plus;Anti-Obesity Compound Library;Targeted Diversity Library; Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose […]