Tag: MDM2 Inhibitor|Inhibitor

For research use only. We do not sell to patients. MX69 CAS No. : 1005264-47-0 Biological Activity：MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. Research Area：Cancer Targets：IAP|MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Peptidomimetic Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Ferroptosis Compound Library;Pyroptosis Compound […]

For research use only. We do not sell to patients. AM-8735 CAS No. : 1429386-01-5 Biological Activity：AM-8735 is a potent and selective MDM2 inhibitor with an IC50 of 25 nM. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Small Molecules:UBE2T/FANCL-IN-1;MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Teslexivir;TRAF6 peptide;Tenovin-6;PK11007;NAcM-OPT;GN25;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. RO-5963 CAS No. : 1416663-77-8 Biological Activity：RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Small Molecules:UBE2T/FANCL-IN-1;MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Teslexivir;TRAF6 peptide;Tenovin-6;PK11007;AM-8735;NAcM-OPT;GN25;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide Trending […]

For research use only. We do not sell to patients. Nutlin-3 CAS No. : 548472-68-0 Biological Activity：Nutlin-3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Peptidomimetic Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Ferroptosis Compound […]

For research use only. We do not sell to patients. PROTAC MDM2 Degrader-2 CAS No. : 2249944-99-6 Biological Activity：PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. Research Area：Cancer Targets：PROTACs|MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. PROTAC MDM2 Degrader-1 CAS No. : 2249944-98-5 Biological Activity：PROTAC MDM2 Degrader-1 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-1 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. Research Area：Cancer Targets：PROTACs|MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. NVP-CGM097 sulfate CAS No. : 1313367-56-4 Biological Activity：NVP-CGM097 sulfate is a potent and selective MDM2 inhibitor with IC50 of 1.7±0.1 nM for hMDM2. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound […]

For research use only. We do not sell to patients. PROTAC MDM2 Degrader-3 CAS No. : 2249750-23-8 Biological Activity：PROTAC MDM2 Degrader-3 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-3 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. Research Area：Cancer Targets：PROTACs|MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. NVP-CGM097 CAS No. : 1313363-54-0 Biological Activity：NVP-CGM097 is a potent and selective MDM2 inhibitor with IC50 of 1.7±0.1 nM for hMDM2. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound […]

For research use only. We do not sell to patients. Idasanutlin CAS No. : 1229705-06-9 Biological Activity：Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC50 of 6 nM. Research Area：Cancer Targets：MDM-2/p53|E1/E2/E3 Enzyme Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer […]