Tag: Inhibitor|Modulator

For research use only. We do not sell to patients. Atazanavir CAS No. : 198904-31-3 Biological Activity：Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir is also a SARS-CoV […]

For research use only. We do not sell to patients. L-Theanine CAS No. : 3081-61-6 Biological Activity：L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through […]

For research use only. We do not sell to patients. Phenyltoloxamine CAS No. : 92-12-6 Biological Activity：Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (Ki: 160 nM)[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：Sigma Receptor|Histamine Receptor|Cytochrome P450 Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Tripelennamine;Brompheniramine-d6 maleate;Hypericin;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Galeterone;Ketotifen fumarate;Ranitidine;BD1063 dhydrochloride;Bergapten;Ginsenoside Rd;Cetirizine;AS1810722;Diphenylpyraline hydrochloride Trending […]

For research use only. We do not sell to patients. γ-Secretase modulator 12 CAS No. : 2204249-82-9 Biological Activity：γ-Secretase modulator 12 (Compound 1a) is a γ-secretase modulator that can selectively decrease amyloid-β42 (Aβ42) levels (IC50 of 0.39 µM). γ-Secretase modulator 12 can be used for Alzheimer’s disease research. γ-Secretase modulator 12 has a good brain/plasma […]

For research use only. We do not sell to patients. Palmatine CAS No. : 3486-67-7 Biological Activity：Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner […]

For research use only. We do not sell to patients. Atazanavir sulfate CAS No. : 229975-97-7 Biological Activity：Atazanavir (BMS-232632) sulfate, a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir sulfate is […]

For research use only. We do not sell to patients. Thevetiaflavone CAS No. : 29376-68-9 Biological Activity：Thevetiaflavone could upregulate the expression of Bcl‑2 and downregulate that of Bax and caspase‑3. Research Area：Neurological Disease Targets：Bcl-2 Family|Caspase Related Small Molecules:BI-3812;Pyridoclax;PUMA BH3 TFA;Dehydrocorydaline;Z-DEVD-AMC;Bufarenogin;Murizatoclax;p-nitro-Pifithrin-α;Obatoclax;ML132;CYD-2-11;BM 957;L67;AKN-028 acetate;(S)-Gossypol (acetic acid);Ossirene;A-385358;Mcl-1 inhibitor 6;S55746;δ-Secretase inhibitor 11;Anticancer agent 63;Fenbufen-d9;MCL-1/BCL-2-IN-2;Penicillic acid;Anticancer agent 65;Sesamolin;(E)-Ferulic acid-d3 Trending […]

For research use only. We do not sell to patients. DCPIB CAS No. : 82749-70-0 Biological Activity：DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker […]

For research use only. We do not sell to patients. BAI1 CAS No. : 335165-68-9 Biological Activity：BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death. Research Area：Cancer Targets：Bcl-2 […]

For research use only. We do not sell to patients. Cyclofenil CAS No. : 2624-43-3 Biological Activity：Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity[2]. Research Area：Infection|Endocrinology Targets：Influenza Virus|Estrogen Receptor/ERR Related […]