Tag: Inhibitor|MDM2 Inhibitor|Inducer

For research use only. We do not sell to patients. Milademetan CAS No. : 1398568-47-2 Biological Activity：Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis[2]. Research Area：Cancer Targets：MDM-2/p53|Apoptosis|E1/E2/E3 Enzyme Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. SAR405838 CAS No. : 1303607-60-4 Biological Activity：SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity[2]. Research Area：Cancer Targets：MDM-2/p53|Apoptosis|E1/E2/E3 Enzyme Related Screening […]