Tag: Inhibitor|Inducer

For research use only. We do not sell to patients. Topoisomerase I inhibitor 3 CAS No. : 2588211-50-9 Biological Activity：Topoisomerase I inhibitor 3 (Compound ZML-14) is a topoisomerase I inhibitor and can interact with topoisomerase I-DNA complex. Topoisomerase I inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase. Research Area：Cancer Targets：Topoisomerase|Apoptosis […]

For research use only. We do not sell to patients. Cinchonine monohydrochloride hydrate CAS No. : 206986-88-1 Biological Activity：Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of […]

For research use only. We do not sell to patients. AMG PERK 44 CAS No. : 1883548-84-2 Biological Activity：AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG […]

For research use only. We do not sell to patients. Ketoprofen-d3 CAS No. : 159490-55-8 Biological Activity：Ketoprofen-d3 (RP-19583-d3) is the deuterium labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively. Research […]

For research use only. We do not sell to patients. Efavirenz-13C6 CAS No. : 1261394-62-0 Biological Activity：Efavirenz-13C6 (DMP 266-13C6) is the 13C-labeled Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative […]

For research use only. We do not sell to patients. Psoralen CAS No. : 66-97-7 Biological Activity：Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al. Research Area：Cancer Targets：Influenza Virus|HIV|Apoptosis Related Screening Libraries:Natural Product Library […]

For research use only. We do not sell to patients. Tubulysin H CAS No. : 799822-09-6 Biological Activity：Tubulysin H is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range[2]. […]

For research use only. We do not sell to patients. VEGFR-IN-3 Biological Activity：VEGFR-IN-3 (compound 3f) is a VEGFR inhibitor. VEGFR-IN-3 inhibits OVCAR-4 and MDA-MB-468 cancer cells growth with IC50s of 0.29 and 0.35 μM, respectively. VEGFR-IN-3 can be used for the research of cancer. Research Area：Cancer Targets：VEGFR|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II […]

For research use only. We do not sell to patients. Glaucocalyxin A CAS No. : 79498-31-0 Biological Activity：Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect. Research Area：Cancer Targets：Akt|Apoptosis|PI3K Related Screening […]

For research use only. We do not sell to patients. Mcl-1 inhibitor 6 CAS No. : 2598978-56-2 Biological Activity：Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a Kd of 0.23 nM and a Ki of 0.02 μM. Mcl-1 inhibitor 6 possesses superior selectivity over other Bcl-2 family […]