Tag: Inhibitor|Antagonist

For research use only. We do not sell to patients. ASTX660 CAS No. : 1799328-86-1 Biological Activity：ASTX660 is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein (cIAP) and X-linked inhibitor of apoptosis protein (XIAP). Research Area：Cancer Targets：IAP|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. Pimozide-d5 N-Oxide CAS No. : 1794795-40-6 Biological Activity：Pimozide-d5 N-Oxide is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with […]

For research use only. We do not sell to patients. Plerixafor CAS No. : 110078-46-1 Biological Activity：Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 […]

For research use only. We do not sell to patients. Oxybutynin chloride CAS No. : 1508-65-2 Biological Activity：Oxybutynin chloride is an oral active and competitive mAChR antagonist with Kis of 14.3 and 5.55 nM for specific [3H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner […]

For research use only. We do not sell to patients. Risperidone-d4 CAS No. : 1020719-76-9 Biological Activity：Risperidone-d4 (R 64 766-d4) is the deuterium labeled Risperidone. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. Research Area：Neurological […]

For research use only. We do not sell to patients. Kuwanon G CAS No. : 75629-19-5 Biological Activity：Kuwanon G is a flavonoid isolated from Morus alba, acts as a bombesin receptor antagonist, with potential antimicrobial activity[2]. Research Area：Infection Targets：Bombesin Receptor|Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole Trending […]

For research use only. We do not sell to patients. Cenicriviroc CAS No. : 497223-25-3 Biological Activity：Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. Research Area：Infection|Endocrinology Targets：HIV|CCR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound […]

For research use only. We do not sell to patients. Chlorprothixene CAS No. : 113-59-7 Biological Activity：Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity. Research Area：Neurological Disease Targets：Dopamine Receptor|Histamine Receptor|Bacterial […]

For research use only. We do not sell to patients. Drotaverine hydrochloride CAS No. : 985-12-6 Biological Activity：Drotaverine (hydrochloride) is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3′,5′-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects. Targets：Phosphodiesterase (PDE)|Calcium […]

For research use only. We do not sell to patients. Metoprolol fumarate CAS No. : 80274-67-5 Biological Activity：Metoprolol fumarate (CGP 2175C) is an orally active, selective β1-adrenoceptor antagonist. Metoprolol fumarate shows anti-inflammation, antitumor and anti-angiogenic properties[2][3]. Research Area：Cancer|Infection|Endocrinology|Cardiovascular Disease Targets：Adrenergic Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Todralazine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;ARC 239 dihydrochloride;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer […]