Tag: Inhibitor|Antagonist

For research use only. We do not sell to patients. Eplerenone CAS No. : 107724-20-9 Biological Activity：Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic […]

For research use only. We do not sell to patients. Rostafuroxin CAS No. : 156722-18-8 Biological Activity：Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity[2][3][4]. Research […]

For research use only. We do not sell to patients. CXCR4 antagonist 1 CAS No. : 675135-69-0 Biological Activity：CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity. Research Area：Infection Targets：CXCR|HIV Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;CXCR4 antagonist 6;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine […]

For research use only. We do not sell to patients. W-54011 CAS No. : 405098-33-1 Biological Activity：W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of […]

For research use only. We do not sell to patients. Flopropione CAS No. : 2295-58-1 Biological Activity：Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor[2]. Flopropione also as an antispasmodic agent[3]. Research Area：Neurological Disease Targets：5-HT Receptor|COMT Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive […]

For research use only. We do not sell to patients. Rimcazole dihydrochloride CAS No. : 75859-03-9 Biological Activity：Rimcazole (BW 234U) dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can attenuate cocaine-induced […]

For research use only. We do not sell to patients. Propiverine-d7 hydrochloride Biological Activity：Propiverine-d7 hydrochloride is the deuterium labeled Propiverine hydrochloride. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence[2]. Research Area：Neurological Disease Targets：Calcium Channel|mAChR Related Small Molecules:VU0357017 […]

For research use only. We do not sell to patients. K777 CAS No. : 233277-99-1 Biological Activity：K777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the […]

For research use only. We do not sell to patients. Verapamil-d3 hydrochloride Biological Activity：Verapamil-d3 ((±)-Verapamil-d3) hydrochloride is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, […]

For research use only. We do not sell to patients. Halopemide CAS No. : 59831-65-1 Biological Activity：Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent[2]. Research Area：Cancer|Neurological Disease Targets：Dopamine Receptor|Phospholipase Related Screening […]