Tag: Inhibitor|Agonist

For research use only. We do not sell to patients. Angiopeptin CAS No. : 113294-82-9 Biological Activity：Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin inhibits […]

For research use only. We do not sell to patients. Butaprost CAS No. : 69685-22-9 Biological Activity：Butaprost is a selective prostaglandin E receptor (EP2) agonist with an EC50 of 33 nM and a Ki of 2.4 μM for murine EP2 receptor. Butaprost is less activity against murine EP1, EP3 and EP4 receptors. Butaprost attenuates fibrosis […]

For research use only. We do not sell to patients. L-Glutamine-2-13C CAS No. : 180991-02-0 Biological Activity：L-Glutamine-2-13C (L-Glutamic acid 5-amide-2-13C) is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2]. […]

For research use only. We do not sell to patients. Imperatorin CAS No. : 482-44-0 Biological Activity：Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. Research Area：Neurological Disease Targets：TRP Channel|Cholinesterase (ChE) Related Screening Libraries:Natural […]

For research use only. We do not sell to patients. L-Glutamine-5-13C CAS No. : 159680-32-7 Biological Activity：L-Glutamine-5-13C (L-Glutamic acid 5-amide-5-13C) is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[2]. […]

For research use only. We do not sell to patients. Branaplam CAS No. : 1562338-42-4 Biological Activity：Branaplam (LMI070; NVS-SM1) is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length […]

For research use only. We do not sell to patients. 4-O-Methyl honokiol CAS No. : 68592-15-4 Biological Activity：4-O-Methyl honokiol is a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist, and inhibtis NF-κB activity, used for cancer and inflammation research. Research Area：Cancer|Inflammation/Immunology Targets：NF-κB|PPAR Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA […]

For research use only. We do not sell to patients. Mosapride citrate dihydrate CAS No. : 636582-62-2 Biological Activity：Mosapride (TAK-370) citrate dehydrate is a gastroprokinetic agent with 5-hydroxytryptamine4 receptor agonist activity and has been widely used in the research of a variety of gastrointestinal disorders. Mosapride citrate dihydrate potently inhibits Kv4.3 in a concentration-dependent manner […]

For research use only. We do not sell to patients. Branaplam hydrochloride CAS No. : 1562338-39-9 Biological Activity：Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. […]

For research use only. We do not sell to patients. Methylprednisolone CAS No. : 83-43-2 Biological Activity：Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3]. Research Area：Cancer|Infection|Endocrinology|Inflammation/Immunology Targets：Autophagy|Glucocorticoid Receptor|Bacterial|SARS-CoV Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]