Tag: Inhibitor|Activator

For research use only. We do not sell to patients. Gymnemic acid I CAS No. : 122168-40-5 Biological Activity：Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress[2]. Research Area：Metabolic Disease Targets：Autophagy|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant […]

For research use only. We do not sell to patients. SKF-96365 hydrochloride CAS No. : 130495-35-1 Biological Activity：SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride […]

For research use only. We do not sell to patients. CUR61414 CAS No. : 334998-36-6 Biological Activity：CUR61414 is a novel, potent and cell permeable Hedgehog signaling pathway inhibitor (IC50 =100-200 nM). CUR61414 is a small-molecule aminoproline class compound and selectively binds to smoothened (Smo) with a Ki  value of 44 nM. CUR-61414 can induce apoptosis in […]

For research use only. We do not sell to patients. Halofuginone CAS No. : 55837-20-2 Biological Activity：Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM[2]. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity[3][4]. Halofuginone is also a […]

For research use only. We do not sell to patients. D-Glutamine CAS No. : 5959-95-5 Biological Activity：D-Glutamine is a cell-permeable D type stereoisomer of Glutamine. Research Area：Metabolic Disease Targets：Ferroptosis|Autophagy|Mitophagy|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Autophagy Compound Library;Human Endogenous Metabolite Compound Library;Anti-Aging Compound Library;Ferroptosis Compound Library;Medicine […]

For research use only. We do not sell to patients. Torin 2 CAS No. : 1223001-51-1 Biological Activity：Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the […]

For research use only. We do not sell to patients. Prinomastat hydrochloride CAS No. : 1435779-45-5 Biological Activity：Prinomastat hydrochloride (AG3340 hydrochloride) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat hydrochloride inhibits MMP-2, MMP-3 and MMP-9 with Kis of […]

For research use only. We do not sell to patients. Atorvastatin hemicalcium salt CAS No. : 134523-03-8 Biological Activity：Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and […]

For research use only. We do not sell to patients. 360A CAS No. : 794458-56-3 Biological Activity：360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay. Research Area：Cancer Targets：Telomerase|G-quadruplex Related Small Molecules:Hypericin;2-Di-1-ASP;Epitalon;Telomerase-IN-1;L2H2-6OTD;Ceramides Mixture;Telomerase-IN-3;MM41;L5-DA;SOP1812;RHPS4;TMPyP4 tosylate;G4/HDAC-IN-1;Pyridostatin hydrochloride;BMVC;Carboxy pyridostatin trifluoroacetate salt;Nemorubicin;Telomerase-IN-2;BMVC2;Cycloastragenol;MST-312 Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. MI-3 CAS No. : 1271738-59-0 Biological Activity：MI-3 (Menin-MLL inhibitor 3) is a potent and high affinity menin-MLL inhibitor with an IC50 of 648 nM and a Kd of 201 nM. Research Area：Cancer Targets：Epigenetic Reader Domain|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone […]