Tag: Inhibitor|Activator

For research use only. We do not sell to patients. Corynoline CAS No. : 18797-79-0 Biological Activity：Corynoline is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2]. Research Area：Inflammation/Immunology|Neurological Disease|Cancer Targets：Keap1-Nrf2|Cholinesterase (ChE) Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Neuronal Signaling […]

For research use only. We do not sell to patients. Saikosaponin A CAS No. : 20736-09-8 Biological Activity：Saikosaponin A is an active component of Bupleurum chinensis, up-regulates LXRα expression, with potent anti-inflammatory activity. Research Area：Inflammation/Immunology|Cancer Targets：LXR|Bacterial Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Glycoside […]

For research use only. We do not sell to patients. Masitinib CAS No. : 790299-79-5 Biological Activity：Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. […]

For research use only. We do not sell to patients. AICAR CAS No. : 2627-69-2 Biological Activity：AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2]. Research Area：Cancer Targets：YAP|Autophagy|Mitophagy|Endogenous Metabolite|AMPK Related Screening […]

For research use only. We do not sell to patients. CUDA CAS No. : 479413-68-8 Biological Activity：CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for […]

For research use only. We do not sell to patients. RRD-251 CAS No. : 72214-67-6 Biological Activity：RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities. Research Area：Cancer Targets：Raf|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Oxygen Sensing Compound […]

For research use only. We do not sell to patients. UNC2400 CAS No. : 1433200-49-7 Biological Activity：UNC2400 is a close analog of UNC1999 with >1,000-fold lower potency than UNC1999 as a negative control for cell-based studies[2]. Research Area：Cancer Targets：Autophagy|Histone Methyltransferase Related Small Molecules:EEDi-5285;EZH2-IN-2;BIX-01294;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;OTS186935 hydrochloride;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740;SMYD2-IN-1;PRMT5-IN-21;Sinefungin;MM-401;SETDB1-TTD-IN-1;Dot1L-IN-2;PRMT5-IN-10;PRMT1-IN-1 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  […]

For research use only. We do not sell to patients. ZM-447439 CAS No. : 331771-20-1 Biological Activity：ZM-447439 is an aurora kinase inhibitor with IC50s of 110 and 130 nM for aurora A and B, respectively. Research Area：Cancer Targets：Aurora Kinase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Anti-Cancer […]

For research use only. We do not sell to patients. Delanzomib CAS No. : 847499-27-8 Biological Activity：Delanzomib (CEP-18770) is a potent and orally active chymotrypsin-like activity of the proteasome inhibitor with an IC50 of 3.8 nM. Delanzomib inhibits NF-κB activity, induces cancer cell apoptotic, and has strong antiangiogenic and anti-cancer activities. Research Area：Cancer Targets：NF-κB|Proteasome|Apoptosis Related […]

For research use only. We do not sell to patients. (+)-Medioresinol CAS No. : 40957-99-1 Biological Activity：(+)-Medioresinol is a furofuran type lignan with antifungal, antibacterial and lesishmanicidal activities. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. (+)-Medioresinol can reduce the cardiovascular disease risk[2]. Research Area：Infection|Neurological Disease|Cardiovascular Disease Targets：Fungal|Reactive Oxygen […]