Tag: Inhibitor|Activator

For research use only. We do not sell to patients. 3,5-Di-tert-butylphenol CAS No. : 1138-52-9 Biological Activity：3,5-Di-tert-butylphenol is an volatile organic compound with anti-biofilm and antifungal activities. 3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species (ROS). Research Area：Infection Targets：Fungal|Reactive Oxygen Species Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;NF-κB […]

For research use only. We do not sell to patients. Saikosaponin D CAS No. : 20874-52-6 Biological Activity：Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β. Research Area：Cancer|Infection|Inflammation/Immunology Targets：NF-κB|STAT|Bacterial|Estrogen Receptor/ERR Related Screening Libraries:Natural Product Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. FLLL32 CAS No. : 1226895-15-3 Biological Activity：FLLL32, a synthetic analog of curcumina, is a JAK2/STAT3 dual inhibitor with anti-tumor activity. FLLL32 can inhibit the induction of STAT3 phosphorylation by IFNα and IL-6 in breast cancer cells[2]. Research Area：Cancer Targets：JAK|STAT|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis […]

For research use only. We do not sell to patients. Saikogenin D CAS No. : 5573-16-0 Biological Activity：Saikogenin D is isolated from Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of […]

For research use only. We do not sell to patients. Ritonavir CAS No. : 155213-67-5 Biological Activity：Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM. Research Area：Infection Targets：HIV|HIV Protease|Apoptosis|SARS-CoV Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. H-89 CAS No. : 127243-85-0 Biological Activity：H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases. Research Area：Neurological Disease Targets：Autophagy|PKA Related Small Molecules:PKI […]

For research use only. We do not sell to patients. YS-49 monohydrate Biological Activity：YS-49 (monohydrate) is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has […]

For research use only. We do not sell to patients. Dutasteride CAS No. : 164656-23-9 Biological Activity：Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT. Research Area：Cancer Targets：5 alpha Reductase|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing […]

For research use only. We do not sell to patients. Tubulin inhibitor 1 CAS No. : 2237054-53-2 Biological Activity：Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis. Research Area：Cancer Targets：Microtubule/Tubulin|Apoptosis Related Screening Libraries:Bioactive Compound Library […]

For research use only. We do not sell to patients. VLX600 CAS No. : 327031-55-0 Biological Activity：VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer activity[2]. Research Area：Cancer Targets：Autophagy|Mitochondrial Metabolism Related Screening […]