Tag: Inhibitor|Activator

For research use only. We do not sell to patients. NU9056 CAS No. : 1450644-28-6 Biological Activity：NU9056 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an [2] of 2 µM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells. Research Area：Cancer Targets：Apoptosis|Histone Acetyltransferase […]

For research use only. We do not sell to patients. GANT 61 CAS No. : 500579-04-4 Biological Activity：GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway. Research Area：Cancer Targets：Gli|Autophagy Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Transcription Factor-Targeted […]

For research use only. We do not sell to patients. Diclofenac potassium CAS No. : 15307-81-0 Biological Activity：Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and […]

For research use only. We do not sell to patients. N-Salicyloyltryptamine CAS No. : 31384-98-2 Biological Activity：N-Salicyloyltryptamine acts on voltage-dependent Na+, Ca2+, and K+ ion channels inhibitor. N-Salicyloyltryptamine inhibits K+ currents with an IC50 value of 34.6 μM (Ito). N-Salicyloyltryptamine also exhibits anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect–[5]. Research Area：Inflammation/Immunology|Neurological Disease Targets：NF-κB|Calcium Channel|Potassium Channel|Guanylate Cyclase|ERK […]

For research use only. We do not sell to patients. FGFR4-IN-7 Biological Activity：FGFR4-IN-7 (Compound C3) is a covalent reversible FGFR4 inhibitor with an IC50 value of 0.42 μM. FGFR4-IN-7 induces apoptosis via the FGFR4 signaling pathway blockage. FGFR4-IN-7 can be used for the research of hepatocellular carcinoma (HCC). Research Area：Cancer Targets：FGFR|Apoptosis Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. Oxibendazole CAS No. : 20559-55-1 Biological Activity：Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities[2]. Research Area：Infection Targets：Parasite|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;FDA Approved & Pharmacopeial Drug Library;Antiparasitic […]

For research use only. We do not sell to patients. Skatole-d3 CAS No. : 111399-60-1 Biological Activity：Skatole-d3 (3-Methylindole-d3) is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. Research Area：Others Targets：Fungal|Autophagy|p38 MAPK|Bacterial|Endogenous Metabolite|Aryl Hydrocarbon Receptor Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Antifungal agent 20;Nicotinamide […]

For research use only. We do not sell to patients. CCT365623 hydrochloride CAS No. : 2126136-98-7 Biological Activity：CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties. […]

For research use only. We do not sell to patients. Jasplakinolide CAS No. : 102396-24-7 Biological Activity：Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and […]

For research use only. We do not sell to patients. Menin-MLL inhibitor MI-2 CAS No. : 1271738-62-5 Biological Activity：Menin-MLL inhibitor MI-2 is a Menin-MLL interaction inhibitor with IC50 of 446±28 nM. Research Area：Cancer Targets：Epigenetic Reader Domain|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Blood Cancer […]