Tag: Inhibitor|Activator

For research use only. We do not sell to patients. PYR-41 CAS No. : 418805-02-4 Biological Activity：PYR-41 is a selective and cell permeable inhibitor of ubiquitin-activating enzyme E1 with an IC50 of < 10 μM, with little activity at E2 and E3. Research Area：Cancer Targets：Apoptosis|E1/E2/E3 Enzyme Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound […]

For research use only. We do not sell to patients. Psoralidin CAS No. : 18642-23-4 Biological Activity：Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties. Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation[2]. Research Area：Cancer Targets：Notch|Reactive Oxygen Species|Bacterial|Lipoxygenase|COX Related Screening Libraries:Natural Product […]

For research use only. We do not sell to patients. Buparlisib Hydrochloride CAS No. : 1312445-63-8 Biological Activity：Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively. Research Area：Cancer Targets：Apoptosis|PI3K Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound […]

For research use only. We do not sell to patients. Amiloride hydrochloride dihydrate CAS No. : 17440-83-4 Biological Activity：Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA[2]). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2[3]) channel. Research Area：Metabolic Disease|Cardiovascular Disease Targets：TRP […]

For research use only. We do not sell to patients. Entinostat CAS No. : 209783-80-2 Biological Activity：Entinostat is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively. Research Area：Cancer Targets：Autophagy|HDAC|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive […]

For research use only. We do not sell to patients. Yatein CAS No. : 40456-50-6 Biological Activity：Yatein is a lignan isolated from A. chilensis, with antiproliferative activity. Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression[2]. Research Area：Cancer|Infection Targets：HSV|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;Isoborneol;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;Vidarabine monohydrate;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II […]

For research use only. We do not sell to patients. Tubulysin D CAS No. : 309935-57-7 Biological Activity：Tubulysin D is one of the most potent derivatives among the tubulysins isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin D is a novel tetrapeptide that displays potent antitumor activity and leads to cell cycle […]

For research use only. We do not sell to patients. (-)-Epicatechin gallate CAS No. : 1257-08-5 Biological Activity：(-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM. Research Area：Cancer Targets：Autophagy|Virus Protease|COX Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Natural Product […]

For research use only. We do not sell to patients. PF-4708671 CAS No. : 1255517-76-0 Biological Activity：PF-4708671 is a potent cell-permeable S6K1 inhibitor with a Ki of 20 nM and IC50 of 160 nM. Research Area：Cancer Targets：Autophagy|Ribosomal S6 Kinase (RSK) Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Autophagy Compound […]

For research use only. We do not sell to patients. 4EGI-1 CAS No. : 315706-13-9 Biological Activity：4EGI-1 is an inhibitor of eIF4E/eIF4G interaction, with a Kd of 25 μM against eIF4E binding. Research Area：Cancer Targets：Autophagy|Eukaryotic Initiation Factor (eIF)|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound […]