Tag: inhibitor

For research use only. We do not sell to patients. KB SRC 4 CAS No. : 1380088-03-8 Biological Activity：KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has […]

For research use only. We do not sell to patients. Tirbanibulin dihydrochloride CAS No. : 1038395-65-1 Biological Activity：Tirbanibulin (dihydrochloride) (KX2-391 (dihydrochloride)) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Research Area：Cancer Targets：Microtubule/Tubulin|Src Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Azlocillin sodium salt CAS No. : 37091-65-9 Biological Activity：Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum[2][3]. Research Area：Infection Targets：Parasite|Bacterial|Antibiotic Related Screening Libraries:Covalent Screening Library […]

For research use only. We do not sell to patients. α-Cyano-4-hydroxycinnamic acid CAS No. : 28166-41-8 Biological Activity：α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted […]

For research use only. We do not sell to patients. Valeriandoid F CAS No. : 1427162-60-4 Biological Activity：Valeriandoid F is an iridoid, which potently inhibits NO production with an IC50 value of 0.88 μM. Valeriandoid F has anti-inflammatory and antiproliferative activities. Research Area：Cancer|Inflammation/Immunology Targets：NO Synthase Related Small Molecules:Carboxy-PTIO potassium;Ciwujianoside C3;NOS-IN-3;Regaloside A;Aminopicoline;trans-Isoferulic acid;DETA NONOate;Chondroitin sulfate;3-Bromo-7-nitroindazole;α7 nAchR-JAK2-STAT3 […]

For research use only. We do not sell to patients. JAK3/BTK-IN-1 CAS No. : 2674036-91-8 Biological Activity：JAK3/BTK-IN-1 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-1 has the potential for the research of JAK3 kinase and/or BTK-related […]

For research use only. We do not sell to patients. BI-135585 CAS No. : 1114561-85-1 Biological Activity：BI-135585 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with an IC50 of 13 nM. BI-135585 exhibits >1000-fold selectivity over other hydroxysteroid dehydrogenases. BI-135585 can be used for type 2 diabetes research[2]. Research Area：Metabolic Disease […]

For research use only. We do not sell to patients. AMG-208 CAS No. : 1002304-34-8 Biological Activity：AMG-208 is an orally active c-Met/RON dual selective inhibitor with an IC50 of 9 nM for c-Met. AMG-208 is a CYP3A4 inhibitor with an IC50 of 32 μM. AMG-208 has anti-cancer activity[2][3]. Research Area：Cancer Targets：c-Met/HGFR|Cytochrome P450 Related Screening Libraries:Drug […]

For research use only. We do not sell to patients. ALK-IN-9 CAS No. : 2359662-39-6 Biological Activity：ALK-IN-9 (compound 40) is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC50s of

For research use only. We do not sell to patients. Icariside F2 CAS No. : 115009-57-9 Biological Activity：Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity. Research Area：Inflammation/Immunology Targets：NF-κB Related Small […]