Tag: inhibitor

For research use only. We do not sell to patients. SCD1 inhibitor-3 CAS No. : 1282606-48-7 Biological Activity：SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer. […]

For research use only. We do not sell to patients. rel-Sertraline-d3 hydrochloride CAS No. : 1330180-66-9 Biological Activity：rel-Sertraline-d3 hydrochloride is the deuterium labeled Sertraline hydrochloride. Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive[2]. Research […]

For research use only. We do not sell to patients. VPC-14449 CAS No. : 1621375-32-3 Biological Activity：VPC-14449 is a potent and selective inhibitor of the DNA-binding domain of the androgen receptor (AR-DBD), with IC50 of 0.34 μM for full-length human AR. VPC-14449 reduces the ability of full-length AR as well as AR variants to interact […]

For research use only. We do not sell to patients. Umbralisib hydrochloride CAS No. : 1532533-78-0 Biological Activity：Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T […]

For research use only. We do not sell to patients. Proguanil-d6 Biological Activity：Proguanil D6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial drug. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent […]

For research use only. We do not sell to patients. AX-024 CAS No. : 1370544-73-2 Biological Activity：AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and […]

For research use only. We do not sell to patients. DPTIP CAS No. : 351353-48-5 Biological Activity：DPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM[2]. Research Area：Inflammation/Immunology Targets：Phospholipase Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Pyroptosis Compound Library;Exosomes Compound Library;Lipid Metabolism Compound […]

For research use only. We do not sell to patients. pUL89 Endonuclease-IN-1 CAS No. : 391680-92-5 Biological Activity：pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 value of 0.88 μM and has antiviral activitiy. Research Area：Infection Targets：CMV Related Small Molecules:Calcium trinatrium diethylenetriaminepentaacetic acid hydrate;Enocitabine;Fomivirsen sodium;Braco-19;Tricin;Ancitabine hydrochloride;Tomeglovir;Bisindolylmaleimide IV;Artemisone;SIRT1-IN-1;ML324;Cyclopropavir;B220;CEF20;FIT-039;Maribavir;Cyclic […]

For research use only. We do not sell to patients. SR9186 CAS No. : 1361414-26-7 Biological Activity：SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to […]

For research use only. We do not sell to patients. Antileishmanial agent-2 Biological Activity：Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251 Trending products：Recombinant Proteins  |  […]