Tag: inhibitor

For research use only. We do not sell to patients. LY2886721 CAS No. : 1262036-50-9 Biological Activity：LY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity […]

For research use only. We do not sell to patients. Sulfadimethoxine-d6 CAS No. : 73068-02-7 Biological Activity：Sulfadimethoxine-d6 (Sulphadimethoxine-d6) is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections. Research Area：Infection Targets：Bacterial|Antibiotic Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;(R)-Camptothecin-d5 Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. Carboxy-PTIO potassium CAS No. : 148819-94-7 Biological Activity：Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model[2][3]. […]

For research use only. We do not sell to patients. C29 CAS No. : 363600-92-4 Biological Activity：C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocks hTLR2/1 and hTLR2/6 signaling with IC50s of 19.7 and 37.6 μM, respectively. Research Area：Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Antioxidant […]

For research use only. We do not sell to patients. Antifungal agent 20 CAS No. : 2460281-94-9 Biological Activity：Antifungal agent 20 exhibits remarkable antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum. Research Area：Infection Targets：Fungal Related Small Molecules:Debneyol;Haloprogin;Staurosporine;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;(R)-Camptothecin-d5;Ticlatone;Aminothiazole;Magnesium silicate;α-Terpinene;Hydroxyphenyllactic acid;Iprobenfos;Chlorphenesin;Moniliformin sodium salt;HLF1-11;β-Amyrin […]

For research use only. We do not sell to patients. (+)-Isopulegol CAS No. : 104870-56-6 Biological Activity：(+)-Isopulegol is a terpenoid found in Mentha canadensis L. (+)-Isopulegol shows phagostimulatory activity towards adults of S. granarius and T. confusum. (+)-Isopulegol is a feeding attractant for adults of T. confusum and T. granarium larvae[2]. Research Area：Infection Targets：Parasite Related […]

For research use only. We do not sell to patients. SJB3-019A CAS No. : 2070015-29-9 Biological Activity：SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM. Research Area：Cancer Targets：Deubiquitinase Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage […]

For research use only. We do not sell to patients. SKF89976A hydrochloride CAS No. : 85375-15-1 Biological Activity：SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Research Area：Neurological Disease Targets：GABA Receptor Related Screening Libraries:Bioactive Compound Library […]

For research use only. We do not sell to patients. Senazodan hydrochloride CAS No. : 98326-33-1 Biological Activity：Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III[2]. Research Area：Cardiovascular Disease Targets：Phosphodiesterase (PDE) Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Colorectal Cancer Compound […]

For research use only. We do not sell to patients. SLN124 Biological Activity：SLN124 is a GalNac-siRNA targeting transmembrane serine protease 6 (Tmprss6). SLN124 is composed of a trimeric GalNAc ligand conjugated to TMPRSS6‐siRNA. SLN124 has the potential for an siRNA to restore hepcidin expression and normalise iron homeostasis in β‐thalassaemia. Research Area：Metabolic Disease Targets：Ser/Thr Protease|Small […]