Tag: Inducer|Inhibitor|Modulator

For research use only. We do not sell to patients. PI-1840 CAS No. : 1401223-22-0 Biological Activity：PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of […]

For research use only. We do not sell to patients. Amantadine sulfate CAS No. : 31377-23-8 Biological Activity：Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has […]

For research use only. We do not sell to patients. Amantadine CAS No. : 768-94-5 Biological Activity：Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. […]

For research use only. We do not sell to patients. Bortezomib CAS No. : 179324-69-7 Biological Activity：Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. […]

For research use only. We do not sell to patients. Amantadine hydrochloride CAS No. : 665-66-7 Biological Activity：Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has […]

For research use only. We do not sell to patients. Apostatin-1 CAS No. : 2559703-06-7 Biological Activity：Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by […]

For research use only. We do not sell to patients. Coenzyme Q0 CAS No. : 605-94-7 Biological Activity：Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound can be derived from Antrodia cinnamomea. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation […]

For research use only. We do not sell to patients. Bortezomib-d8 Biological Activity：Bortezomib-d8 (PS-341-d8) is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome […]

For research use only. We do not sell to patients. Amentoflavone CAS No. : 1617-53-4 Biological Activity：Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase[2][3][4]. Research Area：Cancer|Infection|Inflammation/Immunology|Neurological Disease Targets：Fungal|Reactive Oxygen Species|RSV|Bacterial|GABA Receptor|Apoptosis […]

For research use only. We do not sell to patients. Salinomycin sodium salt CAS No. : 55721-31-8 Biological Activity：Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. […]