Tag: Inducer|Inhibitor|Activator|Modulator

For research use only. We do not sell to patients. Betulinic acid CAS No. : 472-15-1 Biological Activity：Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[2][3][4]. Research Area：Cancer|Infection|Inflammation/Immunology Targets：Parasite|Topoisomerase|Autophagy|NF-κB|HIV|Mitophagy|Endogenous Metabolite|Apoptosis Related Screening Libraries:Natural Product Library Plus;Drug […]

For research use only. We do not sell to patients. Anticancer agent 64 Biological Activity：Anticancer agent 64 (compound 5m) shows cytotoxic activity in CCRF-CEM cells, with IC50 of 2.4 μM. Anticancer agent 64 shows good anticancer activity through apoptosis induction. Anticancer agent 64 induces caspase 3 and 7 activation and PARP cleavage. Anticancer agent 64 […]

For research use only. We do not sell to patients. Bromosporine CAS No. : 1619994-69-2 Biological Activity：Bromosporine is a potent BET inhibitor with an IC50 value of 2.1 μM for PCAF. Bromosporine can arrest cell cycle and induce apoptosis in cancer cells. Bromosporine exhibits excellent antitumor activity in xenograft mice model when combined with 5-FU […]

For research use only. We do not sell to patients. AVN-944 CAS No. : 297730-17-7 Biological Activity：AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and […]

For research use only. We do not sell to patients. Oxychlororaphine CAS No. : 550-89-0 Biological Activity：Oxychloroaphine could be isolated from the bacterium Pantoea agglomerans naturally present in soil. Oxychloroaphine has broad-spectrum antifungal activity. Oxychloroaphine has cytotoxicity in a dose-dependent manner and induces apoptosis. Oxychloroaphine can be used in research of cancer[2]. Research Area：Cancer|Infection Targets：Fungal|PARP|Bcl-2 […]