Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Anisomycin CAS No. : 22862-76-6 Biological Activity：Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. Anisomycin is a JNK activator, which increases phospho-JNK[2][3]. Anisomycin is a bacterial antibiotic[4]. Research Area：Cancer|Infection Targets：Parasite|DNA/RNA […]
For research use only. We do not sell to patients. Piperlongumine CAS No. : 20069-09-4 Biological Activity：Piperlongumine is a alkaloid, possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities[2]. Piperlongumine induces ROS, and induces apoptosis in cancer cell lines. Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway. Piperlongumin […]
For research use only. We do not sell to patients. Isoginkgetin CAS No. : 548-19-6 Biological Activity：Isoginkgetin is a pre-mRNA splicing inhibitor inhibitor. Isoginkgetin also inhibits activities of both Akt, NF-κB and MMP-9. Isoginkgetin inhibits the activity of the 20S proteasome, induces apoptosis and activates autophagy[2]. Research Area：Cancer|Inflammation/Immunology Targets：Akt|Autophagy|NF-κB|MMP|Proteasome|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive […]
For research use only. We do not sell to patients. Valproic acid CAS No. : 99-66-1 Biological Activity：Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits […]
For research use only. We do not sell to patients. Deferoxamine CAS No. : 70-51-9 Biological Activity：Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, […]
For research use only. We do not sell to patients. Deferoxamine mesylate CAS No. : 138-14-7 Biological Activity：Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine […]
For research use only. We do not sell to patients. Anticancer agent 56 CAS No. : 2241915-59-1 Biological Activity：Anticancer agent 56 (compound 4d) is a potent anti-cancer agent with drug-likeness properties, possessing anticancer activity against several cancer cell lines (IC50
For research use only. We do not sell to patients. Sertaconazole CAS No. : 99592-32-2 Biological Activity：Sertaconazole (FI7056 free base) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of […]
For research use only. We do not sell to patients. Valproic acid-d15 CAS No. : 362049-65-8 Biological Activity：Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of […]
For research use only. We do not sell to patients. 2-Methoxyestradiol-d5 CAS No. : 358731-34-7 Biological Activity：2-Methoxyestradiol-d5 is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) […]