Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Sertaconazole nitrate CAS No. : 99592-39-9 Biological Activity：Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration […]
For research use only. We do not sell to patients. Pseudolaric Acid B CAS No. : 82508-31-4 Biological Activity：Pseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes[2][3]. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through […]
For research use only. We do not sell to patients. Valproic acid-d6 CAS No. : 87745-18-4 Biological Activity：Valproic acid-d6 (VPA-d6) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation […]
For research use only. We do not sell to patients. Sulfasalazine-d4 CAS No. : 1346606-50-5 Biological Activity：Sulfasalazine-d4 is the deuterium labeled Sulfasalazine. Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer[2][3][4]. Research Area：Cancer|Infection|Inflammation/Immunology Targets：Ferroptosis|Autophagy|NF-κB|Bacterial|Antibiotic|Apoptosis Related Small […]
For research use only. We do not sell to patients. CDK1/2/4-IN-1 CAS No. : 2414633-49-9 Biological Activity：CDK1/2/4-IN-1 (compound 3a) is a potent CDK inhibitor with IC50 values of 1.47, 0.78 and 0.87 μM for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates Bax, caspase-3, P53 levels […]
For research use only. We do not sell to patients. Ginsenoside Rb1 CAS No. : 41753-43-9 Biological Activity：Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 . Research Area：Inflammation/Immunology|Cancer Targets：HSV|Autophagy|NF-κB|Na+/K+ ATPase|Mitophagy|IRAK Related Screening […]
For research use only. We do not sell to patients. Theophylline monohydrate CAS No. : 5967-84-0 Biological Activity：Theophylline (1,3-Dimethylxanthine) monohydrate is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline (1,3-Dimethylxanthine) monohydrate inhibits PDE3 activity to relax airway smooth muscle. Theophylline (1,3-Dimethylxanthine) monohydrate has anti-inflammatory activity by increase IL-10 and […]
For research use only. We do not sell to patients. Sunitinib Malate CAS No. : 341031-54-7 Biological Activity：Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation […]
For research use only. We do not sell to patients. Honokiol CAS No. : 35354-74-6 Biological Activity：Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier[2][3][4]. Research Area：Cancer Targets：Akt|HCV|Autophagy|ERK […]
For research use only. We do not sell to patients. Valproic acid-d4 CAS No. : 87745-17-3 Biological Activity：Valproic acid-d4 (VPA-d4) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation […]