Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Midostaurin CAS No. : 120685-11-2 Biological Activity：Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[2]. Midostaurin also upregulates endothelial nitric oxide […]
For research use only. We do not sell to patients. Quercetin CAS No. : 117-39-5 Biological Activity：Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively. Research Area：Cancer Targets：Autophagy|Reactive Oxygen Species|Mitophagy|Apoptosis|PI3K […]