Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Catechin-13C3 Biological Activity：Catechin-13C3 ((+)-Catechin-13C3) is the 13C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Research Area：Cancer Targets：Influenza Virus|Endogenous Metabolite|Apoptosis|COX Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;Bomedemstat ditosylate;2-Mercaptobenzothiazole;Akt/NF-κB/JNK-IN-1;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Enpp/Carbonic anhydrase-IN-1;Biliverdin hydrochloride;GK563;Calpeptin;COX-2/5-LOX-IN-3;Lobetyolin;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone monosulfate sodium;25-Hydroxycholesterol-d6 Trending products：Recombinant […]

For research use only. We do not sell to patients. Diclofenac-d4 CAS No. : 153466-65-0 Biological Activity：Diclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM […]

For research use only. We do not sell to patients. Pazopanib-d6 CAS No. : 1219592-01-4 Biological Activity：Pazopanib-d6 (GW786034-d6) is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. Research Area：Cancer Targets：Autophagy|VEGFR|c-Kit|FGFR|PDGFR […]

For research use only. We do not sell to patients. L-779450 CAS No. : 303727-31-3 Biological Activity：L-779450 is a potent and selective B-Raf kinase inhibitor with a Kd of 2.4 nM. Research Area：Cancer Targets：Autophagy|Raf Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Oxygen Sensing Compound Library;Ferroptosis […]

For research use only. We do not sell to patients. Lycorine CAS No. : 476-28-8 Biological Activity：Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a […]

For research use only. We do not sell to patients. STAT3-IN-11 CAS No. : 2503096-50-0 Biological Activity：STAT3-IN-11 (7a) is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes (Survivin and Mcl-1) without affecting its upstream tyrosine kinases (Src and JAK2) levels and p-STAT1 expression. […]

For research use only. We do not sell to patients. SY-5609 CAS No. : 2417302-07-7 Biological Activity：SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). SY-5609 induces apoptosis in tumor cells and has […]

For research use only. We do not sell to patients. Tofacitinib citrate CAS No. : 540737-29-9 Biological Activity：Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities. Research Area：Cancer|Infection|Inflammation/Immunology Targets：JAK|Fungal|Influenza Virus|Bacterial|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Bafilomycin C1 CAS No. : 88979-61-7 Biological Activity：Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi[2]. Bafilomycin C1 induces cell apoptosis and […]

For research use only. We do not sell to patients. Terrein CAS No. : 582-46-7 Biological Activity：Terrein is a melanogenesis inhibitor. Terrein induces apoptosis in breast cancer cell lines [2]. Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa[3]. Research Area：Cancer Targets：Antibiotic|Melanocortin Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Leucomycin;BJE6-106;Dinaciclib;Ecteinascidin […]