Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. MG-115 CAS No. : 133407-86-0 Biological Activity：MG-115 is a potent and reversible proteasome inhibitor, with Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis[2][3]. Research Area：Cancer Targets：Proteasome|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Lamotrigine-13C3,d3 CAS No. : 1246815-13-3 Biological Activity：Lamotrigine-13C3,d3 (LTG-13C3,d3) is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research […]

For research use only. We do not sell to patients. Targaprimir-96 TFA Biological Activity：Targaprimir-96 TFA is a potent inhibitor of microRNA-96 (miR-96) processing. Targaprimir-96 TFA selectively modulates miR-96 production in cancer cells and triggers apoptosis. Targaprimir-96 TFA binds primary miR-96 (pri-miR-96) with low nanomolar affinity. Targaprimir-96 TFA directly engages pri-miR-96 in breast cancer cells and […]

For research use only. We do not sell to patients. Pogostone CAS No. : 23800-56-8 Biological Activity：Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml [2]. Pogostone induces cell apoptosis and autophagy[2]. Research […]

For research use only. We do not sell to patients. NKP-1339 CAS No. : 197723-00-5 Biological Activity：NKP-1339 (IT-139; KP-1339) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. NKP-1339 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. NKP-1339 has a […]

For research use only. We do not sell to patients. Erlotinib-13C6 CAS No. : 1211107-68-4 Biological Activity：Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Research Area：Cancer Targets：EGFR|Autophagy Related Small Molecules:NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;Genistein;Epertinib hydrochloride;UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;HER2-IN-6;PROTAC EGFR […]

For research use only. We do not sell to patients. Carfilzomib CAS No. : 868540-17-4 Biological Activity：Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells. Research Area：Cancer Targets：Autophagy|Proteasome|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus; Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. Pim-1 kinase inhibitor 1 CAS No. : 2803505-57-7 Biological Activity：Pim-1 kinase inhibitor 1 is a Pim-1 kinase inhibitor with an IC50 of 0.11 μM for Pim-1 kinase. Pim-1 kinase inhibitor 1 shows anticancer activity to several cancer cell lines by promotes cell apoptosis. Pim-1 kinase […]

For research use only. We do not sell to patients. Eugenol-d3 CAS No. : 1335401-17-6 Biological Activity：Eugenol-d3 is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation. Research Area：Infection|Inflammation/Immunology|Cancer Targets：Parasite|Ferroptosis|Reactive Oxygen Species|Bacterial|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;(+)-Isopulegol;Bomedemstat ditosylate;Sandramycin;Chitoheptaose […]

For research use only. We do not sell to patients. Cinchonine hydrochloride CAS No. : 5949-11-1 Biological Activity：Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells. Research Area：Cancer Targets：Parasite|Apoptosis Related Small Molecules:Physalin A;(+)-Isopulegol;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;SR9186;Antileishmanial agent-2;Azlocillin […]