Inducer|Antagonist|Agonist - epigenetics modulation frontier

Kynurenic acid

Posted on January 14, 2023 by haoyuan2014

For research use only. We do not sell to patients. Kynurenic acid CAS No. : 492-27-3 Biological Activity：Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. Research Area：Inflammation/Immunology|Neurological Disease|Endocrinology Targets：CXCR|GPR35|Endogenous Metabolite|Apoptosis|iGluR Related Screening Libraries:Natural Product Library Plus;Clinical Compound Library […]

T0901317

Posted on January 13, 2023 by haoyuan2014

For research use only. We do not sell to patients. T0901317 CAS No. : 293754-55-9 Biological Activity：T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXRα. T0901317 activates FXR with an EC50 of 5 μM[2]. T0901317 is RORα and RORγ dual inverse agonist with Ki values of […]