Tag: Inducer|Agonist

For research use only. We do not sell to patients. Alda-1 CAS No. : 349438-38-6 Biological Activity：Alda-1 is a potent and selective ALDH2 agonist, which activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. Research Area：Cancer Targets：Aldehyde Dehydrogenase (ALDH)|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. (Rac)-Norepinephrine-d3 (formate) Biological Activity：(Rac)-Norepinephrine-d3 (formate) is deuterium labeled Norepinephrine. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[2][3][4]. Research Area：Endocrinology|Cardiovascular Disease Targets：Adrenergic Receptor|Autophagy|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone […]

For research use only. We do not sell to patients. VDR agonist 1 CAS No. : 2269494-43-9 Biological Activity：VDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC50 of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes […]

For research use only. We do not sell to patients. Cabergoline-d6 CAS No. : 2738376-76-4 Biological Activity：Cabergoline-d6 is deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively). Research Area：Endocrinology Targets：Dopamine Receptor|Autophagy Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 […]

For research use only. We do not sell to patients. 9-cis-Retinoic acid CAS No. : 5300-03-8 Biological Activity：9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities[2][3][4][5]. Research Area：Cancer|Inflammation/Immunology|Neurological Disease Targets：RAR/RXR|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Nicotinamide N-oxide;3-Hydroxyglutaric […]

For research use only. We do not sell to patients. Methyl 3,4-dihydroxybenzoate-d3-1 CAS No. : 2733147-54-9 Biological Activity：Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect. Research Area：Cancer|Inflammation/Immunology Targets：Keap1-Nrf2|Apoptosis Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. Norepinephrine tartrate CAS No. : 51-40-1 Biological Activity：Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors[2][3][4]. Research Area：Endocrinology|Cardiovascular Disease Targets：Adrenergic Receptor|Autophagy|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone […]

For research use only. We do not sell to patients. Capsaicin CAS No. : 404-86-4 Biological Activity：Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects[2]. Research Area：Cancer Targets：Autophagy|TRP Channel|Endogenous Metabolite|Apoptosis Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Betamethasone-d5-1 CAS No. : 2244574-92-1 Biological Activity：Betamethasone-d5-1 is deuterium labeled Betamethasone. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis[2][3][4]. Research Area：Inflammation/Immunology|Endocrinology|Cancer Targets：Glucocorticoid Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor […]

For research use only. We do not sell to patients. Ingenol 3,20-dibenzoate CAS No. : 59086-90-7 Biological Activity：Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de […]