Tag: Inducer

For research use only. We do not sell to patients. Mimosine CAS No. : 500-44-7 Biological Activity：Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity. Mimosine is a known chelator of Fe(III)[2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells[3]. Anti-cancer, […]

For research use only. We do not sell to patients. Poncirin CAS No. : 14941-08-3 Biological Activity：Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models. Research Area：Inflammation/Immunology Targets：Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus; Apoptosis Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. 27-O-(tert-Butyldimethylsilyl)withaferin A CAS No. : 1392820-18-6 Biological Activity：27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide, is an apoptosis inducer. 27-O-(tert-Butyldimethylsilyl)withaferin A shows antiproliferative activity against HeLa, A-549 and MCF-7 human cancer cell lines, and against normal Vero cells. Research Area：Cancer Targets：Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic […]

For research use only. We do not sell to patients. Gracillin CAS No. : 19083-00-2 Biological Activity：Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent. Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1] Research Area：Cancer Targets：Apoptosis Related Screening Libraries:Natural […]

For research use only. We do not sell to patients. Beta-Sitosterol (purity>80%) CAS No. : 83-46-5 Biological Activity：Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation. Research Area：Cancer|Inflammation/Immunology|Cardiovascular Disease Targets：Endogenous […]

For research use only. We do not sell to patients. (S)-Thalidomide CAS No. : 841-67-8 Biological Activity：(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-enantiomer of Thalidomide. (S)-Thalidomide has immunomodulatory, anti-inflammatory, antiangiogenic and pro-apoptotic effects[2][3]. (S)-Thalidomide induces teratogenic effects by binding to cereblon (CRBN) [4]. Research Area：Metabolic Disease|Inflammation/Immunology Targets：Apoptosis|Molecular Glues Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. Enterodiol CAS No. : 80226-00-2 Biological Activity：Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Anti-cancer activities[2]. Research Area：Cancer Targets：Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid […]

For research use only. We do not sell to patients. PACAP-38 (31-38), human, mouse, rat TFA Biological Activity：PACAP-38 (31-38), human, mouse, rat TFA is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat TFA elevates cytosolic Ca2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal […]

For research use only. We do not sell to patients. Anticancer agent 45 Biological Activity：Anticancer agent 46 (compound 2b) is a potent and selective anticancer agent. Anticancer agent 46 shows cytotoxicity activity in cancer cells. Anticancer agent 46 induces apoptosis. Anticancer agent 46 shows low toxicity towards activated lymphocytes of human blood. Research Area：Cancer Targets：Apoptosis […]

For research use only. We do not sell to patients. Paederosidic acid CAS No. : 18842-98-3 Biological Activity：Paederosidic acid is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis. Research Area：Cancer Targets：Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Natural Product Library;Anti-Cancer Compound […]