Tag: Antagonist|Inhibitor

For research use only. We do not sell to patients. Azelastine-13C,d3 Biological Activity：Azelastine-13C,d3 is deuterium labeled Azelastine. Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[2][3][4]. Research Area：Infection|Endocrinology|Metabolic Disease|Inflammation/Immunology Targets：Histamine Receptor|SARS-CoV Related Small Molecules:Tripelennamine;SARS-CoV-2-IN-33;Brompheniramine-d6 maleate;GRL-0496;Samelisant;Chlorphenoxamine;Grazoprevir potassium salt;H3 […]

For research use only. We do not sell to patients. Doxofylline-d6 CAS No. : 1219805-99-8 Biological Activity：Doxofylline-d6 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV. Research Area：Inflammation/Immunology Targets：Phosphodiesterase (PDE)|Adenosine Receptor Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;Deltarasin hydrochloride;Glaucine;MRS 1523;Ziritaxestat;APNEA;Udenafil-d7;D159687;MIPS521;Derenofylline;ITI-214;FSCPX;PDE10-IN-5;Theobromine-d3;ICI 153110;Furamidine dihydrochloride;Inosine-13C;ML-030;Norisoboldine;PDE4-IN-10 Trending products：Recombinant […]

For research use only. We do not sell to patients. ONO-8130 CAS No. : 459841-96-4 Biological Activity：ONO-8130 is an orally active and selective prostanoid EP1 receptor antagonist. ONO-8130 blocks phosphorylation of ERK in the L6 spinal cord. ONO-8130 relieves bladder pain in mice with cyclophosphamide-induced cystitis. ONO-8130 can be used for interstitial cystitis research. Research […]

For research use only. We do not sell to patients. DC260126 CAS No. : 346692-04-4 Biological Activity：DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 could protect MIN6 β cells from […]

For research use only. We do not sell to patients. Chloropyramine hydrochloride CAS No. : 6170-42-9 Biological Activity：Chloropyramine hydrochloride is a histamine receptor H1 antagonist which can also inhibit the biochemical function of VEGFR-3 and FAK. Research Area：Cancer|Endocrinology Targets：VEGFR|Histamine Receptor|FAK Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus; FDA-Approved Drug Library Mini;Bioactive Compound […]

For research use only. We do not sell to patients. REV 5901 CAS No. : 101910-24-1 Biological Activity：REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene […]

For research use only. We do not sell to patients. HF50731 CAS No. : 2484771-19-7 Biological Activity：HF50731 (compound 21) is a potent CXCR4 antagonist. HF50731 shows strong CXCR4 binding affinity, with IC50 of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, and HIV-1 infection via CXCR4 coreceptor, with IC50 values of 119.2 nM, 621.4 […]

For research use only. We do not sell to patients. Aminophylline CAS No. : 317-34-0 Biological Activity：Aminophylline is a competitive and non-selective phosphodiesterase (PDE) inhibitor. Aminophylline is a competitive adenosine receptor antagonist. Aminophylline has apulmonary vasodilator action as well as a bronchodilator action and has the potential for asthma research[2]. Research Area：Inflammation/Immunology|Cancer Targets：Phosphodiesterase (PDE)|Adenosine Receptor […]

For research use only. We do not sell to patients. Plerixafor octahydrochloride CAS No. : 155148-31-5 Biological Activity：Plerixafor octahydrochloride (AMD3100 octahydrochloride) is a selective CXCR4 antagonist with an IC50 of 44 nM. Research Area：Inflammation/Immunology|Endocrinology|Cancer Targets：CXCR|HIV|Virus Protease Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;GPCR/G Protein […]

For research use only. We do not sell to patients. T 82 CAS No. : 252264-92-9 Biological Activity：T 82 is a potent 5-HT3 antagonist and acetylcholinesterase (AChE) inhibitor, used for treatment of Alzheimer’s Disease. Research Area：Neurological Disease Targets：5-HT Receptor|Cholinesterase (ChE) Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Piperilate;Renzapride;BuChE-IN-5;LY 344864 racemate;Harmine hydrochloride;AChE/BChE-IN-10;Valerenic acid;Timosaponin AIII;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Trimyristin;AChE-IN-10;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride Trending products：Recombinant Proteins  […]