Tag: Antagonist|Inducer

For research use only. We do not sell to patients. PEAQX tetrasodium hydrate Biological Activity：PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B, respectively. Research Area：Neurological Disease Targets：Apoptosis|iGluR Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Membrane […]

For research use only. We do not sell to patients. Dexbrompheniramine CAS No. : 132-21-8 Biological Activity：Dexbrompheniramine is an orally active H1 receptor antagonist. Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine. Dexbrompheniramine can be used for the research of hay fever and urticaria. Research Area：Inflammation/Immunology Targets：Histamine Receptor|Endogenous Metabolite Related Small […]

For research use only. We do not sell to patients. Tolvaptan CAS No. : 150683-30-0 Biological Activity：Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be […]

For research use only. We do not sell to patients. Bicalutamide-d4 CAS No. : 1185035-71-5 Biological Activity：Bicalutamide-d4 is the deuterium labeled Bicalutamide. Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer. Research Area：Cancer Targets：Androgen Receptor|Autophagy Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;RD162;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU 58841;Triptophenolide;ARD-61;Dehydroisoandrosterone 3-acetate;Topilutamide;CSRM617 hydrochloride;ARD-2128;A4B17;MK-0773;LH-RH II […]

For research use only. We do not sell to patients. MRS 2578 CAS No. : 711019-86-2 Biological Activity：MRS 2578 is a selective and potent P2Y6 receptor antagonist with IC50s of 37 nM (human) and 98 nM (rat). MRS 2578 exhibits insignificant activity at P2Y1, P2Y2, P2Y4, and P2Y11 receptors[2]. Research Area：Cardiovascular Disease Targets：P2Y Receptor|Apoptosis Related […]

For research use only. We do not sell to patients. Nifedipine CAS No. : 21829-25-4 Biological Activity：Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Calcium Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound […]

For research use only. We do not sell to patients. Spironolactone-d7 Biological Activity：Spironolactone-d7 (SC9420-d7) is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[2][3]. […]

For research use only. We do not sell to patients. Spironolactone-d3-1 Biological Activity：Spironolactone-d3-1 is deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[2][3]. Research Area：Metabolic […]

For research use only. We do not sell to patients. Spironolactone-d3 Biological Activity：Spironolactone-d3 (SC9420-d3) is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[2][3]. […]

For research use only. We do not sell to patients. Xevinapant hydrochloride CAS No. : 1071992-57-8 Biological Activity：Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with Kis of 66.4, 1.9, and 5.1 nM, […]