Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Fingolimod CAS No. : 162359-55-9 Biological Activity：Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant. Research Area：Cancer|Inflammation/Immunology Targets：PAK|LPL Receptor Related Screening Libraries:Natural Product-like Compound Library;Drug […]
For research use only. We do not sell to patients. R 59-022-d5 Biological Activity：R 59-022-d5 (DKGI-I-d5) is the deuterium labeled R 59-022. R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic […]
For research use only. We do not sell to patients. TP508 TFA Biological Activity：TP508 TFA is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates production of NO in human endothelial cells. TP508 TFA activates endothelial cells and […]
For research use only. We do not sell to patients. Spironolactone CAS No. : 52-01-7 Biological Activity：Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[2][3]. Research Area：Metabolic Disease|Cancer […]
For research use only. We do not sell to patients. SP2509 CAS No. : 1423715-09-6 Biological Activity：SP2509 is a potent and selective antagonist of lysine specific demethylase 1 (LSD1) with an IC50 of 13 nM. Research Area：Cancer Targets：Apoptosis|Histone Demethylase Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Anti-Blood […]
For research use only. We do not sell to patients. Etalocib CAS No. : 161172-51-6 Biological Activity：Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis[2][3]. Research Area：Cancer|Inflammation/Immunology Targets：Leukotriene […]
For research use only. We do not sell to patients. Spiperone hydrochloride CAS No. : 2022-29-9 Biological Activity：Spiperone hydrochloride (Spiroperidol hydrochloride) is a selective dopamine D2 receptor (Ki values of 0.06 nM, 0.6 nM, 0.08 nM, ~350 nM, ~3500 nM for D2, D3, D4, D1 and D5 receptors, respectively) and 5-HT2A/5-HT1A receptor (Kis of 1 […]