Tag: Antagonist

For research use only. We do not sell to patients. Estriol-d3 CAS No. : 79037-36-8 Biological Activity：Estriol-d3 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Research Area：Cancer Targets：Estrogen Receptor/ERR|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic […]

For research use only. We do not sell to patients. Atopaxar hydrobromide CAS No. : 474550-69-1 Biological Activity：Atopaxar (E5555) hydrobromide is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar hydrobromide, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrobromide can be used for the research of atherothrombotic disease[2]. Research […]

For research use only. We do not sell to patients. Saralasin CAS No. : 34273-10-4 Biological Activity：Saralasin ([Sar1,Ala8] Angiotensin II) is an octapeptide analog of angiotensin II. Saralasin is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. […]

For research use only. We do not sell to patients. Linzagolix CAS No. : 935283-04-8 Biological Activity：Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix can be used for uterine fibroids, endometriosis, adenomyosis research. Research Area：Cancer|Inflammation/Immunology Targets：GnRH Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G […]

For research use only. We do not sell to patients. NEP(1-40) TFA Biological Activity：NEP(1-40) TFA is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition. Research Area：Inflammation/Immunology Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant […]

For research use only. We do not sell to patients. AZD1283 CAS No. : 919351-41-0 Biological Activity：AZD1283 is a potent P2Y12 receptor antagonist with a binding IC50 of 11 nM and a GTPγS IC50 of 25 nM. AZD1283 has excellent antiplatelet aggregation potency. AZD1283 can be used to research thromboembolic disorders[2]. Research Area：Cardiovascular Disease Targets：P2Y […]

For research use only. We do not sell to patients. AMG 487 (S-enantiomer) CAS No. : 473720-30-8 Biological Activity：AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3. Research Area：Others Targets：CXCR Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:Nicotinamide N-oxide;FC131;CXCR4 antagonist 2;CXCR4 antagonist 6;CXCR2 […]

For research use only. We do not sell to patients. MEN11467 CAS No. : 214487-46-4 Biological Activity：MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK1 receptor antagonist. Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy Netupitant;SB-222200;Senktide;GR 87389;Hemokinin 1, human;Neurokinin A TFA;Imnopitant dihydrochloride;[Glp6] Substance P (6-11);[Lys5,MeLeu9,Nle10]-NKA(4-10) […]

For research use only. We do not sell to patients. Paliperidone CAS No. : 144598-75-4 Biological Activity：Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against […]

For research use only. We do not sell to patients. ERRγ Inverse Agonist 1 CAS No. : 2316832-86-5 Biological Activity：ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist, with an IC50 of 40 nM. Research Area：Cancer Targets：Estrogen Receptor/ERR Related Small Molecules:DS20362725;LSD1/ER-IN-1;Giredestrant;Avobenzone;Estriol-d3;Chrysin;(R)-DPN;MPP hydrochloride;GPR30 agonist-1;Diethylstilbestrol;Endoxifen;Glicoricone;ERB-196;Dihydroresveratrol;FLTX1;(Rac)-Hexestrol-d6 Trending products：Recombinant […]