Tag: Antagonist

For research use only. We do not sell to patients. BPTU CAS No. : 870544-59-5 Biological Activity：BPTU (BMS-646786) is a non-nucleotide P2Y1 receptor allosteric antagonist with antithrombotic activity. BPTU is able to block the P2Y1 receptor located at the neuromuscular junction of the gastrointestinal tract[2]. Research Area：Cancer|Neurological Disease Targets：P2Y Receptor Related Screening Libraries:Covalent Screening Library […]

For research use only. We do not sell to patients. Pavinetant CAS No. : 941690-55-7 Biological Activity：Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist. Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Anti-COVID-19 […]

For research use only. We do not sell to patients. Vazegepant hydrochloride CAS No. : 1414976-20-7 Biological Activity：Vazegepant (BHV-3500) hydrochloride is a highly soluble CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride is the first intranasal gepant for migraine. Vazegepant hydrochloride may be helpful in effective management of COVID-19 associated pulmonary inflammation[2][3]. Research Area：Infection|Inflammation/Immunology […]

For research use only. We do not sell to patients. SB-568849 CAS No. : 395679-53-5 Biological Activity：SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7. Research Area：Metabolic Disease|Endocrinology Targets：MCHR1 (GPR24) Related Small Molecules:[Ala17]-MCH;AZD1979;ALB-127158(a);ATC0175;MCH(human, mouse, rat);BMS-819881;MCHR1 antagonist 1;MCHR1 antagonist 2;Ethyl linolenate;Melanin Concentrating Hormone, salmon;SNAP 94847;GW-803430;MCH-1 antagonist 1;NGD-4715;MCHR1 antagonist 3;TC-MCH 7c;Ac-hMCH(6-16)-NH2;Neuropeptide […]

For research use only. We do not sell to patients. Ziprasidone hydrochloride monohydrate CAS No. : 138982-67-9 Biological Activity：Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist. Ziprasidone hydrochloride monohydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM). Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor […]

For research use only. We do not sell to patients. Alfuzosin-d3 CAS No. : 1006724-55-5 Biological Activity：Alfuzosin-d3 is deuterium labeled Alfuzosin. Research Area：Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  […]

For research use only. We do not sell to patients. DG-041 CAS No. : 861238-35-9 Biological Activity：DG-041 is a potent, high affinity and selective EP3 receptor antagonist with IC50s of 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively. DG-041 inhibits PGE2 facilitation of platelet aggregation. DG-041 crosses the blood-brain barrier[2]. Research […]

For research use only. We do not sell to patients. SB-277011 dihydrochloride CAS No. : 1226917-67-4 Biological Activity：SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0,

For research use only. We do not sell to patients. Ipratropium-d7 bromide Biological Activity：Ipratropium-d7 (Sch 1000-d7) bromideis the deuterium labeled Ipratropium bromide. Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist, with binding IC50 values of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide can be used […]

For research use only. We do not sell to patients. Epinastine-13C,d3 hydrobromide Biological Activity：Epinastine-13C,d3 (hydrobromide) is the 13C- and deuterium labeled Epinastine. Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action[2][3][4]. Research Area：Inflammation/Immunology|Endocrinology Targets：Histamine […]