Tag: Antagonist

For research use only. We do not sell to patients. Zaurategrast ethyl ester sulfate CAS No. : 1214261-78-5 Biological Activity：Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. Research Area：Inflammation/Immunology Targets：Integrin Related Small Molecules:GRGDSPK;Integrin Binding Peptide;Cyclo(Arg-Gly-Asp-D-Phe-Cys);HSDVHK-NH2;Lifitegrast sodium;TC-I 15;α2β1 […]

For research use only. We do not sell to patients. LPA5 antagonist 2 Biological Activity：LPA5 antagonist 2 (compound 65) is a high aqueous solubility LPA5 (lysophosphatidic acid receptor 5) antagonist. LPA5 antagonist 2 significantly attenuates nociceptive hypersensitivity and it can be used for the research of inflammatory and neuropathic pains. Research Area：Inflammation/Immunology|Neurological Disease Targets：Others Related […]

For research use only. We do not sell to patients. Ziprasidone amino acid CAS No. : 1159977-64-6 Biological Activity：Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist. Ziprasidone exhibits potent effects of antipsychotic activity . Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor Related Small […]

For research use only. We do not sell to patients. Tirofiban hydrochloride monohydrate CAS No. : 150915-40-5 Biological Activity：Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by […]

For research use only. We do not sell to patients. Adenosine receptor antagonist 1 CAS No. : 2682930-40-9 Biological Activity：Adenosine receptor antagonist 1 is a A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selective for A2aR than A2bR. Research Area：Cancer Targets：Adenosine Receptor Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR […]

For research use only. We do not sell to patients. FSCPX CAS No. : 156547-56-7 Biological Activity：FSCPX is a potent and selective irreversible antagonist of A1 adenosine receptor (A1AR), with low nanomolar potency for binding to the A1AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level […]

For research use only. We do not sell to patients. Losartan-d3 Carboxylic Acid CAS No. : 1189729-40-5 Biological Activity：Losartan-d3 Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM[2]. Research Area：Cardiovascular Disease|Endocrinology|Cancer Targets：Angiotensin Receptor Related Small […]

For research use only. We do not sell to patients. CP-060 CAS No. : 180090-15-7 Biological Activity：CP-​060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities. Research Area：Cardiovascular Disease Targets：Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;MRS 1523;Nilvadipine;Lercanidipine;Anipamil-d25 hydrochloride;ISX-9;ω-Conotoxin MVIIC;Catharanthine;Thapsigargin;Tetrandrine;Ginsenoside Rd;Manidipine dihydrochloride;ω-Agatoxin IVA;AE0047 Hydrochloride;PDE1-IN-4 […]

For research use only. We do not sell to patients. ONC206 CAS No. : 1638178-87-6 Biological Activity：ONC206 is an analogue of TRAIL inducer ONC201. ONC206 is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 has broad-spectrum anti-tumor activity[2]. Research Area：Cancer|Neurological Disease Targets：Dopamine Receptor Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. IRL 2500 CAS No. : 169545-27-1 Biological Activity：IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo. Research Area：Cardiovascular Disease […]