Tag: Agonist|Modulator

For research use only. We do not sell to patients. Nuciferine CAS No. : 475-83-2 Biological Activity：Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at […]

For research use only. We do not sell to patients. Brexpiprazole S-oxide CAS No. : 1191900-51-2 Biological Activity：Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM […]

For research use only. We do not sell to patients. Pindolol CAS No. : 13523-86-9 Biological Activity：Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM). Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor|5-HT Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug […]

For research use only. We do not sell to patients. 27-Hydroxycholesterol CAS No. : 20380-11-4 Biological Activity：27-Hydroxycholesterol is a selective estrogen receptor modulator and an agonist of the liver X receptor. Research Area：Cancer Targets：LXR|Estrogen Receptor/ERR|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Human Endogenous Metabolite Compound Library;Lipid […]

For research use only. We do not sell to patients. SKF 83959 hydrobromide CAS No. : 67287-95-0 Biological Activity：SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist. SKF83959 hydrobromide Ki values for rat D1, D5, D2 and D3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent […]

For research use only. We do not sell to patients. Blarcamesine CAS No. : 195615-83-9 Biological Activity：Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome. Targets：mAChR|Sigma Receptor Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;BD1063 dhydrochloride;Navafenterol saccharinate;DREADD […]

For research use only. We do not sell to patients. Brexpiprazole S-oxide D8 Biological Activity：Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and […]