Tag: Agonist|Inhibitor

For research use only. We do not sell to patients. Pioglitazone hydrochloride CAS No. : 112529-15-4 Biological Activity：Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Research Area：Cancer|Metabolic Disease Targets：Ferroptosis|PPAR Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. L-Glutamine-15N2,d5 Biological Activity：L-Glutamine-15N2,d5 (L-Glutamic acid 5-amide-15N2,d5) is the deuterium and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[2]. Research Area：Metabolic […]

For research use only. We do not sell to patients. L-Glutamine-d5 CAS No. : 14341-78-7 Biological Activity：L-Glutamine-d5 (L-Glutamic acid 5-amide-d5) is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some […]

For research use only. We do not sell to patients. L-Glutamine-13C5,15N2,d5 CAS No. : 2123439-02-9 Biological Activity：L-Glutamine-13C5,15N2,d5 (L-Glutamic acid 5-amide-13C5,15N2,d5) is the deuterium, 13C-, and 15-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation […]

For research use only. We do not sell to patients. Cyprodinil-13C6 CAS No. : 1773496-63-1 Biological Activity：Cyprodinil-13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, […]

For research use only. We do not sell to patients. Vilazodone Hydrochloride CAS No. : 163521-08-2 Biological Activity：Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. Research Area：Neurological Disease Targets：5-HT Receptor|Serotonin Transporter Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G […]

For research use only. We do not sell to patients. Clomethiazole CAS No. : 533-45-9 Biological Activity：Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus[2]. Research Area：Neurological Disease Targets：GABA Receptor|Cytochrome […]

For research use only. We do not sell to patients. Amitriptyline-d6 hydrochloride CAS No. : 203645-63-0 Biological Activity：Amitriptyline-d6 hydrochloride is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline […]

For research use only. We do not sell to patients. Ginsenoside Rg5 CAS No. : 186763-78-0 Biological Activity：Ginsenoside Rg5 is the main component of Red ginseng. Ginsenoside blocks binding of IGF-1 to its receptor with an IC50 of ~90 nM. Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding […]

For research use only. We do not sell to patients. Fluticasone propionate-d5 CAS No. : 1093258-28-6 Biological Activity：Fluticasone propionate-d5 is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid […]