Tag: Agonist|Inhibitor

For research use only. We do not sell to patients. Amitraz-d6 CAS No. : 2734300-36-6 Biological Activity：Amitraz-d6 (BTS-27419-d6) is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis. Research Area：Infection|Endocrinology Targets：Parasite|Adrenergic Receptor|Monoamine […]

For research use only. We do not sell to patients. FSL-1 TFA Biological Activity：FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection. FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells[2]. Research Area：Infection Targets：HSV|Antibiotic|MMP|Toll-like Receptor (TLR) Related Small Molecules:C29;Sandramycin;Isoborneol;Oritavancin;Monascorubrin;TMX-201;Azlocillin sodium salt;Herbimycin A;Leucomycin;Vidarabine monohydrate;Nafcillin;Staurosporine;WAY-170523;Clotrimazole-d5;SQ109;(R)-Camptothecin-d5;Neomycin […]

For research use only. We do not sell to patients. DSP-1053 benzenesulfonate CAS No. : 1176326-78-5 Biological Activity：DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity. Research Area：Neurological Disease Targets：5-HT Receptor|Serotonin Transporter […]

For research use only. We do not sell to patients. Tyrphostin 25 CAS No. : 118409-58-8 Biological Activity：Tyrphostin 25 (AG82) is a specific inhibitor of the EGFR tyrosine kinase. Tyrphostin 25 is also a GPR35 agonist with an IC50 of 0.94 µM and an EC50 of 5.3 µM[2]. Research Area：Cancer|Inflammation/Immunology Targets：EGFR|GPR35 Related Small Molecules:NSC81111;pp60 (v-SRC) […]

For research use only. We do not sell to patients. Dimaprit dihydrochloride CAS No. : 23256-33-9 Biological Activity：Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion[2]. Research Area：Endocrinology Targets：Histamine Receptor|NO Synthase Related Small Molecules:Carboxy-PTIO potassium;Valeriandoid F;Ciwujianoside C3;NOS-IN-3;Regaloside A;Tripelennamine;Brompheniramine-d6 […]

For research use only. We do not sell to patients. (Thr4,Gly7)-Oxytocin CAS No. : 60786-59-6 Biological Activity：(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. [2]. Research Area：Neurological Disease Targets：Oxytocin Receptor|Potassium Channel Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 […]

For research use only. We do not sell to patients. Beclometasone dipropionate monohydrate CAS No. : 77011-63-3 Biological Activity：Beclometasone dipropionate monohydrate, the prodrug of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma […]

For research use only. We do not sell to patients. DY131 CAS No. : 95167-41-2 Biological Activity：DY131 (GSK 9089) is a potent and selective ERRγ and ERRβ agonist. DY131displays inactive against ERRα, ERα and ERβ[2]. DY131 also inhibits Smo signaling[3]. Research Area：Cancer|Endocrinology Targets：Smo|Estrogen Receptor/ERR Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound […]

For research use only. We do not sell to patients. Zaprinast CAS No. : 37762-06-4 Biological Activity：Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs). Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately[2]. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects[3]. Research Area：Neurological […]

For research use only. We do not sell to patients. β-Naphthoflavone CAS No. : 6051-87-2 Biological Activity：β-Naphthoflavone is a non-carcinogenic AhR agonist as a positive control for the induction of AhR transcriptional activity. β-Naphthoflavone inhibits hydrogen peroxide-induced apoptosis[2]. Research Area：Cancer|Neurological Disease Targets：Apoptosis|Aryl Hydrocarbon Receptor Related Screening Libraries:Natural Product-like Compound Library;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation […]