Tag: Agonist|Antagonist

For research use only. We do not sell to patients. Quetiapine CAS No. : 111974-69-7 Biological Activity：Quetiapine (ICI204636) is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the […]

For research use only. We do not sell to patients. TIK-301 CAS No. : 118702-11-7 Biological Activity：TIK-301 (PD-6735) is a chlorinated melatonin derivative and a potent, high-affinity and orally active melatonin MT1 and MT2 receptors agonist with Kis of 0.081 nM and 0.042 nM, respectively. TIK-301 is also a 5-HT2B/5-HT2C receptors antagonist with antidepressant action. […]

For research use only. We do not sell to patients. Rotigotine Hydrochloride CAS No. : 125572-93-2 Biological Activity：Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and […]

For research use only. We do not sell to patients. Isoxsuprine hydrochloride CAS No. : 579-56-6 Biological Activity：Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor|iGluR Related Screening Libraries:Drug […]

For research use only. We do not sell to patients. Agomelatin-d3 CAS No. : 1079389-38-0 Biological Activity：Agomelatin-d3 (S-20098-d3) is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine is a selective 5-HT2C […]

For research use only. We do not sell to patients. Urapidil CAS No. : 34661-75-1 Biological Activity：Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor|5-HT Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved […]

For research use only. We do not sell to patients. Ursodeoxycholic acid-13C CAS No. : 63296-46-8 Biological Activity：Ursodeoxycholic acid-13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential […]

For research use only. We do not sell to patients. 7-Desmethyl-3-hydroxyagomelatine CAS No. : 166527-00-0 Biological Activity：7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[2]. Research Area：Neurological Disease Targets：5-HT Receptor|Melatonin Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;Melatonin-d3;LY 344864 racemate;Harmine hydrochloride;Valerenic acid;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 […]

For research use only. We do not sell to patients. Piribedil D8 CAS No. : 1398044-45-5 Biological Activity：Piribedil D8 (ET-495 D8) is the deuterium labeled Piribedil, which is an antiparkinsonian agent. Research Area：Endocrinology|Neurological Disease Targets：Dopamine Receptor|Adrenergic Receptor Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Todralazine;Bromopride-d3;ARC 239 dihydrochloride;Nuciferine;Yohimbine;Glaucine;Salbutamol;SB-277011 dihydrochloride;BI-167107;Talibegron hydrochloride;MIF-1 TFA;Arotinolol;Sulpiride;(Rac)-Razpipadon;SR59230A;Clebopride malate Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Agomelatine (L(+)-Tartaric acid) CAS No. : 824393-18-2 Biological Activity：Agomelatine L(+)-Tartaric acid (S-20098 L(+)-Tartaric acid) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine L(+)-Tartaric acid is a selective […]