Tag: Agonist

For research use only. We do not sell to patients. Diethylstilbestrol CAS No. : 56-53-1 Biological Activity：Diethylstilbestrol (Stilbestrol), a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. Target: Estrogen Receptor/ERR Diethylstilbestrol (DES), a synthetic estrogen that was used in pregnancy, is a prototype endocrine-disrupting chemical. Although prenatal exposure to DES is […]

For research use only. We do not sell to patients. Deflazacort CAS No. : 14484-47-0 Biological Activity：Deflazacort, a glucocorticoid, is an inactive prodrug and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant. Research Area：Inflammation/Immunology|Endocrinology Targets：Glucocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus; FDA-Approved Drug Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. AM8936 Biological Activity：AM8936 acts as a balanced and potent cannabinoid receptor type-1 (CB1) agonist in functional assays (EC50s of 8.6 and 1.4 nM for rCB1 and hCB1, respectively). AM8936 exhibits high affinity for rat CB1 (rCB1) with Ki of 0.55 nM. AM8936 is a potent […]

For research use only. We do not sell to patients. β-Lipotropin (60-65) CAS No. : 60117-19-3 Biological Activity：β-Lipotropin (60-65) (β-LPH (60-65)), an opioid peptide, is a potent opioid agonist. Research Area：Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;GSK1521498 free base;Trimebutine-d5 fumarate;Dynorphin B (1-13) (TFA);Dermorphin Analog;β-Endorphin (6-31), human;JTC-801;Valorphin;Corydaline;TAN-452;Matrine;Naloxonazine dihydrochloride;[Leu5]-Enkephalin;Sec-O-Glucosylhamaudol;DPDPE;EST73502;CTOP;β-Endorphin, equine;Tyr-W-MIF-1;Nociceptin (1-13), amide […]

For research use only. We do not sell to patients. PF-4878691 CAS No. : 532959-63-0 Biological Activity：PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities[2]. Research Area：Infection|Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:C29;TMX-201;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist […]

For research use only. We do not sell to patients. Higenamine hydrochloride CAS No. : 11041-94-4 Biological Activity：Higenamine hydrochloride (Norcoclaurine hydrochloride), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine hydrochloride (Norcoclaurine hydrochloride) has anti-apoptotic effects[2]. Research […]

For research use only. We do not sell to patients. TRβ agonist 1 CAS No. : 2770681-85-9 Biological Activity：TRβ agonist 1 is a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, with an EC50 value of 21 nM. TRβ agonist 1 can be used for researching dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone […]

For research use only. We do not sell to patients. Pramipexole dihydrochloride CAS No. : 104632-25-9 Biological Activity：Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride can […]

For research use only. We do not sell to patients. Cholic acid 7-sulfate CAS No. : 60320-05-0 Biological Activity：Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholic acid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion. Research Area：Metabolic Disease Targets：G protein-coupled Bile Acid Receptor […]

For research use only. We do not sell to patients. Sauvagine CAS No. : 74434-59-6 Biological Activity：Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine […]